Evidence map›Paper›PMID 35788031›Full record

Trial reportArchives of disease in childhood. Fetal and neonatal edition2023

Feasibility of and experience using a portable MRI scanner in the neonatal intensive care unit.

Maura E Sien, Amie L Robinson, Houchun H Hu, Chris R Nitkin, Ara S Hall, Marcie G Files, Nathan S Artz, John T Pitts, Sherwin S Chan

Registry-linked trialOpen access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Archives of disease in childhood. Fetal and neonatal edition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04629469 (Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Patients), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04629469 narecruitingnot on this map

Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Patients

TypeinterventionalSponsorChildren's Mercy Hospital Kansas CityRan2020 to 2030Enrolled250ConditionsConditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head UltrasoundArmsHyperfine MRI
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. MRI and Implant Safety at Low-Field and Ultralow-Field Strengths.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  5. Review
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  7. Review
  8. Review
  9. Article
  10. Article
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  13. Article
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  15. Article
  16. Article
  17. Article
  18. Article
  19. Low-field MRI: A report on the 2022 ISMRM workshop.Magnetic resonance in medicine · 2023
    Review
  20. Brain imaging with portable low-field MRI.Nature reviews bioengineering · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maura E SienDepartment of Radiology, Children's Mercy, Kansas City, Missouri, USA.ORCID http://orcid.org/0000-0002-4324-3120
Amie L RobinsonDepartment of Radiology, Children's Mercy, Kansas City, Missouri, USA.
Houchun H HuHyperfine, Guilford, Connecticut, USA.
Chris R NitkinDepartment of Pediatrics, Children's Mercy, Kansas City, Missouri, USA.
Ara S HallDepartment of Pediatrics, Children's Mercy, Kansas City, Missouri, USA.
Marcie G FilesDepartment of Pediatrics, Children's Mercy, Kansas City, Missouri, USA.
Nathan S ArtzDepartment of Radiology, Children's Mercy, Kansas City, Missouri, USA.
John T PittsHyperfine, Guilford, Connecticut, USA.
Sherwin S ChanDepartment of Radiology, Children's Mercy, Kansas City, Missouri, USA sschan@cmh.edu.ORCID http://orcid.org/0000-0002-2393-8355
Children's Mercy Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA portable, low-field MRI system is now Food and Drug Administration cleared and has been shown to be safe and useful in adult intensive care unit settings. No neonatal studies have been performed. The objective is to assess our preliminary experience and assess feasibility of using the portable MRI system at the bedside in a neonatal intensive care unit (NICU) at a quaternary children's hospital. STUDY

designThis was a single-site prospective cohort study in neonates ≥2 kg conducted between October and December 2020. All parents provided informed consent. Neonates underwent portable MRI examination in the NICU with support equipment powered on and attached to the neonate during the examination. A paediatric radiologist interpreted each portable MRI examination. The study outcome variable was percentage of portable MRI examinations completed without artefacts that would hinder diagnosis. Findings were compared between portable MRI examinations and standard of care examinations.

resultsEighteen portable, low-field MRI examinations were performed on 14 neonates with an average age of 29.7 days (range 1-122 days). 94% (17 of 18) of portable MRI examinations were acquired without significant artefact. Significant intracranial pathology was visible on portable MRI, but subtle abnormalities were missed. The examination reads were concordant in 59% (10 of 17) of cases and significant pathology was missed in 12% (2 of 17) of cases.

conclusionThis single-centre series demonstrated portable MRI examinations can be performed safely with standard patient support equipment present in the NICU. These findings demonstrate that portable MRI could be used in the future to guide care in the NICU setting. TRIAL REGISTRATION NUMBER: NCT04629469.

Indexed as

Intensive Care Units, NeonatalMagnetic Resonance ImagingClinical CompetenceFeasibility StudiesHumansInfant, NewbornProspective Studiesintensive care units, neonatalMagnetic Resonance Imagingneurologypaediatrics

Identifiers

PMID35788031
PMCPMC9763199
OpenAlexW4283797070

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.