Evidence map›Paper›PMID 35787783›Full record

ArticleBasic and clinical andrology2022

Subfertile patients underestimate their risk factors of reprotoxic exposure.

Nadia Nouiakh, Claire Sunyach, Sarah-Lyne Jos, Irène Sari-Minodier, Catherine Metzler-Guillemain, Blandine Courbiere, Florence Bretelle, Jeanne Perrin

Open access · goldAbstract read
In one paragraph

Article in Basic and clinical andrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nadia NouiakhCentre Clinico-Biologique d'AMP-CECOS, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Claire SunyachPlateforme CREER, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Sarah-Lyne JosCentre Clinico-Biologique d'AMP-CECOS, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Irène Sari-MinodierPlateforme CREER, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Catherine Metzler-GuillemainCentre Clinico-Biologique d'AMP-CECOS, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Blandine CourbiereCentre Clinico-Biologique d'AMP-CECOS, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Florence BretellePlateforme CREER, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France.
Jeanne PerrinCentre Clinico-Biologique d'AMP-CECOS, AP-HM La Conception University Hospital, 147 bd Baille, 13005, Marseille, France. jeanne.perrin@univ-amu.fr.ORCID http://orcid.org/0000-0002-8198-4886
Centre National de la Recherche Scientifique · FRHôpital de la Conception · FRInserm · FRMéditerranée Infection Foundation · FR

Funding

Agence Nationale de la Recherche 11-IDEX-0001-02
6 · The paper itself

Abstract

backgroundExposure of men and women to environmental reprotoxic agents is associated with impaired fertility and pregnancy rates after assisted reproductive treatment (ART). Nevertheless, such exposures are generally not systematically assessed in current practice before ART and subfertile men are generally less explored than women. Our objective was to study subfertile men and women's level of knowledge about reprotoxic agents, their perception of their own risk factors and the correlation between perceived and identified circumstances of exposure.

resultsIn our public university hospital, 390 subfertile patients (185 men and 185 women) requiring assisted reproduction technique (ART) treatment, completed a self-report questionnaire before consultation, in order to assess patients' knowledge of reprotoxic exposures, sources of information about them and perception of their own circumstances of exposure. Then a standardized questionnaire was used by the physician during the consultation to estimate domestic, environmental and occupational risk factors of reprotoxic exposures (RFRE). We compared the patients' perception of exposure with the estimated RFRE. The reprotoxic agents knowledge score of patients was 61%. Their main sources of information were the media (40%), the internet (22%) and gynecologists (15%). The standardized questionnaire identified RFRE in 265/390 patients (68%); risk factor was statistically more frequent in men (77%) than in women (59%) (p < 0.05). In total, 141 of the 265 patients with identified RFRE (53%) were aware of their risk factor of reprotoxic exposure.

conclusionWe identified risk factors of reprotoxic exposures in the majority of subfertile patients, more frequently in men than in women, and half of patients were not aware of their exposures. Patients' main sources of information were extra medical. Efforts should be made to inform patients, especially men, about potential reprotoxic exposure and to enhance medical training about reprotoxic agents, as recommended by international guidelines. The detection and correction of environmental exposures in subfertile men could improve their fecundity, but also their general health, which has been shown to be poorer than health of fertile men.

Indexed as

Assisted reproductive techniqueCouple infertilityEnvironmental exposureMale fertilityMan’s healthOccupational exposure

Identifiers

PMID35787783
PMCPMC9254517
OpenAlexW4283807628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.