Evidence map›Paper›PMID 35787693›Full record

Trial reportCannabis and cannabinoid research2022

A Randomized, Triple-Blind, Comparator-Controlled Parallel Study Investigating the Pharmacokinetics of Cannabidiol and Tetrahydrocannabinol in a Novel Delivery System, Solutech, in Association with Cannabis Use History.

Volker Berl, Yasmin L Hurd, Bruce H Lipshutz, Markus Roggen, Eric J Mathur, Malkanthi Evans

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cannabis and cannabinoid research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06578455 (A Randomized, Open-Label, 4-Way Crossover, Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06578455 phase1completednot on this mapstarted 2024, after this paper: background citation

A Randomized, Open-Label, 4-Way Crossover, Pharmacokinetic Study to Compare CBD-NE to Epidyolex in Healthy Adult Volunteers Under Both Fed and Fasted Conditions

TypeinterventionalSponsordsm-firmenich Switzerland AGRan2024 to 2024Enrolled32ConditionsCBD Pharmacokinetics, Healthy ParticipantsArmsCannabidiol (CBD) Powder, Cannabidiol 100 MG/ML [Epidiolex]
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Cannabidiol at the crossroads: panacea, placebo, or problem?Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  5. Review
  6. Article
  7. HarnessingPharmaceutics · 2024
    Review
  8. Review
  9. Edible marijuana and cycle ergometer exercise.Frontiers in physiology · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Volker BerlNew Age Ventures, New York, New York, USA.ORCID 0000-0002-0665-2718
Yasmin L HurdDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Addiction Institute of Mount Sinai, New York, New York, USA.
Bruce H LipshutzDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, California, USA.
Markus RoggenDelic Labs, Vancouver, Canada.
Eric J MathurBiome Sciences, Inc., Encinitas, California, USA.
Malkanthi EvansKGK Science, Inc., London, Canada.
Critical Systems Labs · CAFreedom to Live · USIcahn School of Medicine at Mount Sinai · USNautilus Ventures · USSciencetech (Canada) · CAUniversity of California, Santa Barbara · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CannabidiolCannabisDronabinolHumansResearch DesignSmokingCannabidiolDronabinolcannabidiolnovel delivery systempharmacokineticstetrahydrocannabinol

Identifiers

PMID35787693
PMCPMC9784610
OpenAlexW4283836187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.