ArticleJournal of medical Internet research2022
StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials.
Article in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Mobile App-Based Tracking of Daily Explicit and Implicit Sense of Agency Among Adults Living in Japan: Longitudinal Observational Study.JMIR formative research · 2026Observational
- Digital N-of-1 trials and their application in experimental physiology.Experimental physiology · 2026Review
- Evaluating the Effectiveness of Nonpharmacological Self-Management Interventions for Persistent Pain: Protocol for Single-Case Experimental Designs.JMIR research protocols · 2026Article
- Article
- Digital Health as an Enabler of Personalized Medicine in Ghana: Gaps, Opportunities, and Future Directions.Journal of medical Internet research · 2026Article
- N-of-1 trials in clinical research: Methodological foundations, statistical approaches and implementation challenges.British journal of clinical pharmacology · 2026Review
- Evaluation of two easy-to-implement digital breathing interventions in the context of daily stress levels in a series of N-of-1 trials: results from the Anti-Stress Intervention Among Physicians (ASIP) study.NPJ digital medicine · 2026Article
- Instrumental variable approach to estimating individual causal effects in N-of-1 trials: application to ISTOP study.Biostatistics (Oxford, England) · 2025Article
- N -of-1 Trials in Nephrology : Moving beyond Case Series.Journal of the American Society of Nephrology : JASN · 2025Article
- Open Source Web Application (HealthTest) for Emotional Health and Wellness Management in University Students: Development and Usability Study.Online journal of public health informatics · 2025Article
- Harnessing n-of-1 trials for personalised paediatric care in the era of information overload.The Lancet. Child & adolescent health · 2025Article
- Evaluation of easy-to-implement anti-stress interventions in a series of N-of-1 trials: study protocol of the anti-stress intervention among physicians study.Frontiers in psychiatry · 2024Article
- Development of the ehive Digital Health App: Protocol for a Centralized Research Platform.JMIR research protocols · 2023Article
- THE VALUE OF N-OF-1 DATA IN ZOOLOGICAL MEDICINE: A METHODOLOGICAL REVIEW.Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2023Review
- N-of-1 trials: The epitome of personalized medicine?Journal of clinical and translational science · 2023Article
- Article
- Conduct and Implementation of Personalized Trials in Research and Practice.Harvard data science review · 2022Article
- Therapeutic Fasting as a Novel Approach to Mitigate Musculoskeletal Symptoms in Breast Cancer Patients undergoing Aromatase Inhibitor Therapy: A Feasibility Study Protocol.Integrative cancer therapiesArticle
- How to design digital health interventions with artificial intelligence: A scoping review.Digital healthReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.