Evidence map›Paper›PMID 35787455›Full record

ArticleAcademic pediatrics

Parent Attitudes Towards Childhood Vaccines After the Onset of SARS-CoV-2 in the United States.

Douglas J Opel, Anna Furniss, Chuan Zhou, John D Rice, Heather Spielvogle, Christine Spina, Cathryn Perreira, Jessica Giang, Nicolas Dundas, Amanda Dempsey and 3 more

Open access · greenAbstract read
In one paragraph

Article in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Navigating parental attitudes on childhood vaccination in Jordan: a cross-sectional study.International journal of environmental health research · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Douglas J OpelDepartment of Pediatrics (DJ Opel), University of Washington School of Medicine and Center for Clinical and Translational Research, Seattle Children's Research Institute, Seattle, Wash. Electronic address: douglas.opel@seattlechildrens.org.
Anna FurnissAdult and Child Consortium for Health Outcomes Research and Delivery Science (A Furniss, JD Rice, C Spina, C Perreira, A Dempsey, and S O'Leary), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colo.
Chuan ZhouDepartment of Pediatrics (C Zhou), University of Washington School of Medicine and Center for Child Health Behavior and Development, Seattle Children's Research Institute, Seattle, Wash.
John D RiceAdult and Child Consortium for Health Outcomes Research and Delivery Science (A Furniss, JD Rice, C Spina, C Perreira, A Dempsey, and S O'Leary), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colo.
Heather SpielvogleCenter for Clinical and Translational Research (H Spielvogle, J Giang, N Dundas), Seattle Children's Research Institute, Seattle, Wash.
Christine SpinaAdult and Child Consortium for Health Outcomes Research and Delivery Science (A Furniss, JD Rice, C Spina, C Perreira, A Dempsey, and S O'Leary), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colo.
Cathryn PerreiraAdult and Child Consortium for Health Outcomes Research and Delivery Science (A Furniss, JD Rice, C Spina, C Perreira, A Dempsey, and S O'Leary), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colo.
Jessica GiangCenter for Clinical and Translational Research (H Spielvogle, J Giang, N Dundas), Seattle Children's Research Institute, Seattle, Wash.
Nicolas DundasCenter for Clinical and Translational Research (H Spielvogle, J Giang, N Dundas), Seattle Children's Research Institute, Seattle, Wash.
Amanda DempseyAdult and Child Consortium for Health Outcomes Research and Delivery Science (A Furniss, JD Rice, C Spina, C Perreira, A Dempsey, and S O'Leary), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colo.
Barbara PahudUniversity of Missouri Kansas City (B Pahud), School of Medicine, Kansas City, Mo.
Jeffrey RobinsonDepartment of Communication (J Robinson), Portland State University, Portland, Ore.
Sean O'LearyAdult and Child Consortium for Health Outcomes Research and Delivery Science (A Furniss, JD Rice, C Spina, C Perreira, A Dempsey, and S O'Leary), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colo.
Outcomes Research Consortium · USSeattle Children's Hospital · USPortland State University · USUniversity of Missouri–Kansas City · US

Funding

Evaluation of the Presumptively Initiating Vaccines and Optimizing Talk with Motivational Interviewing (PIVOT with MI) InterventionR01HD093628 · NICHD · UNIVERSITY OF COLORADO DENVER · PI O'LEARY, SEAN T, OPEL, DOUGLAS J · 2018 to 2022
$3.1M
NICHD NIH HHS R01 HD093628
6 · The paper itself

Abstract

objectiveTo understand the influence of a novel infectious disease epidemic on parent general attitudes about childhood vaccines.

methodsWe conducted a natural experiment utilizing cross-sectional survey data from parents of infants in Washington and Colorado participating in a larger trial that began on September 27, 2019. At enrollment, parents completed the short version of the Parental Attitudes about Childhood Vaccines (PACV-SF), a validated survey scored from 0 to 4, with higher scores representing more negative attitudes. The exposure variable was onset of the SARS-CoV-2 pandemic in the United States, with the before-period defined as September 27, 2019 to February 28, 2020 and the after-period defined as April 1, 2020-December 10, 2020, with the after-period further separated into proximate (April 1, 2020-July 31, 2020) and distant periods (August 1, 2020-December 10, 2020). The outcome variable was parent negative attitudes about childhood vaccines, defined as a score of ≥2 on the PACV-SF. We estimated the probability of the outcome after (vs before) the exposure using log-binomial regression with generalized estimating equations adjusted for demographic confounding variables.

resultsAmong 4562 parents, the risk of negative attitudes was lower immediately after (vs before) SARS-CoV-2 onset (adjusted risk ratio [aRR] = 0.58; 95% confidence interval [CI], 0.36, 0.94; P = .027), but by August-December 2020, the average rate of negative attitudes was 35% higher than during April-July 2020 (aRR: 1.35; 95% CI: 1.13, 1.61; P = .0009).

conclusionsA reduced risk of negative general vaccine attitudes observed immediately after SARS-CoV-2 onset was quickly attenuated.

Indexed as

COVID-19VaccinesChildCross-Sectional StudiesHealth Knowledge, Attitudes, PracticeHumansInfantParentsPatient Acceptance of Health CareSARS-CoV-2United StatesVaccinationVaccinespediatricspreventive medicinepublic healthvaccines

Identifiers

PMID35787455
PMCPMC9249407
OpenAlexW4283781577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.