Evidence map›Paper›PMID 35787178›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2022

Epinephrine evokes shortening of human airway smooth muscle cells following β

Brian T Deeney, Gaoyuan Cao, Sarah Orfanos, Jordan Lee, Mengyuan Kan, Blanca E Himes, Vishal Parikh, Cynthia J Koziol-White, Steven S An, Reynold A Panettieri

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Precision Aptamers Against a Native GPCR through Ligand-Guided Selection.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Skin-lung axis in the atopic march: The immune link from skin to lungs.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Brian T DeeneyRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.ORCID 0000-0002-1472-2245
Gaoyuan CaoRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.
Sarah OrfanosRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.ORCID 0000-0002-8229-8562
Jordan LeeThe Joint Graduate Program in Toxicology, Department of Pharmacology and Toxicology, Rutgers-Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey.
Mengyuan KanDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Blanca E HimesDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Vishal ParikhRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.
Cynthia J Koziol-WhiteRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.
Steven S AnRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.
Reynold A PanettieriRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, New Jersey.ORCID 0000-0003-0834-4636
Rutgers, The State University of New Jersey · USUniversity of Pennsylvania · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9M
TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
CEBPD-Mediated Mechanisms of Glucocorticoid Insensitivity in Severe AsthmaR01HL133433 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HIMES, BLANCA E · 2017 to 2021
$3.2M
NCATS NIH HHS UL1 TR003017NHLBI NIH HHS P01 HL114471NHLBI NIH HHS R01 HL133433NIEHS NIH HHS P30 ES005022NIEHS NIH HHS T32 ES007148
6 · The paper itself

Abstract

Epinephrine (EPI), an endogenous catecholamine involved in the body's fight-or-flight responses to stress, activates α

Indexed as

Myocytes, Smooth MuscleReceptors, Adrenergic, beta-2Adrenergic beta-AgonistsBronchiBronchodilator AgentsEpinephrineHumansMuscle, SmoothReceptors, Adrenergic, alpha-1ADRA1B protein, humanAdrenergic beta-AgonistsBronchodilator AgentsEpinephrineReceptors, Adrenergic, alpha-1Receptors, Adrenergic, beta-2adrenergic receptorsairway smooth muscleasthmabronchospasmcatecholamines

Identifiers

PMID35787178
PMCPMC9359643
OpenAlexW4283811877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.