Evidence map›Paper›PMID 35786746›Full record

ArticleExperimental brain research2022

MEG neural signature of sexual trauma in women veterans with PTSD.

Lisa M James, Arthur F Leuthold, Apostolos P Georgopoulos

Abstract read
PubMed Publisher
In one paragraph

Article in Experimental brain research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lisa M JamesThe PTSD Research Group, Brain Sciences Center (11B), Department of Veterans Affairs Health Care System, One Veterans Drive, Minneapolis, MN, USA. lmjames@umn.edu.
Arthur F LeutholdThe PTSD Research Group, Brain Sciences Center (11B), Department of Veterans Affairs Health Care System, One Veterans Drive, Minneapolis, MN, USA.
Apostolos P GeorgopoulosThe PTSD Research Group, Brain Sciences Center (11B), Department of Veterans Affairs Health Care System, One Veterans Drive, Minneapolis, MN, USA.
University of Minnesota Medical Center · US

Funding

U.S. Department of Veterans Affairs CX001045
6 · The paper itself

Abstract

Previous research has documented the utility of synchronous neural interactions (SNI) in classifying women veterans with and without posttraumatic stress disorder (PTSD) and other trauma-related outcomes based on functional connectivity using magnetoencephalography (MEG). Here, we extend that line of research to evaluate trauma-specific PTSD neural signatures with MEG in women veterans. Participants completed diagnostic interviews and underwent a task-free MEG scan from which SNI was computed. Thirty-five women veterans were diagnosed with PTSD due to sexual trauma and sixteen with PTSD due to non-sexual trauma. Strength of SNI was compared in women with and without sexual trauma, and linear discriminant analysis was used to classify the brain patterns of women with PTSD due to sexual trauma and non-sexual trauma. Comparison of SNI strength between the two groups revealed widespread hypercorrelation in women with sexual trauma relative to those without sexual trauma. Furthermore, using SNI, the brains of participants were classified as sexual trauma or non-sexual trauma with 100% accuracy. These findings bolster evidence supporting the utility of task-free SNI and suggest that neural signatures of PTSD are trauma-specific.

Indexed as

Stress Disorders, Post-TraumaticVeteransBrainBrain MappingFemaleHumansMagnetoencephalographyBiomarkerMagnetoencephalographyPosttraumatic stress disorderSexual trauma

Identifiers

PMID35786746
OpenAlexW4283801517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.