Evidence map›Paper›PMID 35786582›Full record

ArticleEuropean endodontic journal2022

Diabetes Mellitus Affects the Microhardness of Root Dentine: An in-vitro Study.

Mohammad Ali Saghiri, Behnam Rahmani, Michael Conte, Devyani Nath, Ove Peters, Steven Morgano

Abstract read
In one paragraph

Article in European endodontic journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad Ali SaghiriDepartment of Restorative Dentistry, Rutgers Faculty of Dental Medicine, New Jersey, USA / Department of Endodontics, University of the Pacific, Arthur A. Dugoni Faculty of Dentistry, California, USA.
Behnam RahmaniSector of Angiogenesis Regenerative Medicine, Dr. Hajar Afsar Lajevardi Research Group (ADMD), New Jersey, USA.
Michael ConteDepartment of Restorative Dentistry, Clinical Affairs, Rutgers Faculty of Dental Medicine, New Jersey, USA.
Devyani NathDepartment of Restorative Dentistry, Biomaterials and Prosthodontics Laboratory, Rutgers Faculty of Dental Medicine, New Jersey, USA.
Ove PetersDepartment of Endodontics, University of the Pacific, Arthur A. Dugoni Faculty of Dentistry, California, USA; Oral Health Centre, University of Queensland, Brisbane, Australia.
Steven MorganoDepartment of Restorative Dentistry, Rutgers Faculty of Dental Medicine, New Jersey, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was undertaken to compare microhardness and erosion susceptibility of root dentine in teeth extracted from diabetic and non-diabetic donors after the application of different root canal irrigants.

methodsForty-eight single-rooted premolars with single canals (24 each from diabetic and non-diabetic) were selected, and root canals were shaped by using rotary ProTaper files. Dentine slices of 4 mm were transversely sectioned from the middle root third. Specimens were assigned to four subgroups (n=6) and irrigated for 5 minutes: 1) 2.6% sodium hypochlorite (NaOCl); 2) 17% ethylenediaminetetraacetic acid (EDTA); 3) 2% chlorhexidine (CHX); and 4) normal saline. Surface microhardness was determined at 100- and 500-µm depths from the pulp-dentine interface. Scanning electron microscope (SEM) was used to determine the severity of dentine erosion. Data were analyzed by using two-way ANOVA, Post-hoc Tukey's, and Chi-square tests (P<0.05).

resultsDiabetes as well as NaOCl and EDTA decreased surface microhardness of dentine significantly (P<0.05). Diabetes had little effect on the erosion susceptibility of dentine (P>0.05).

conclusionRoot canal irrigants can significantly lower the microhardness; specifically, in diabetic patients, and may be a factor affecting the longevity of root canal-treated teeth.

Indexed as

Diabetes MellitusRoot Canal IrrigantsDental Pulp CavityDentinEdetic AcidHumansEdetic AcidRoot Canal Irrigants

Identifiers

PMID35786582
PMCPMC9285991

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.