Trial reportEuropean endodontic journal2022
Comparative Evaluation of Preemptive and Preventive Analgesic Effect of Oral Ibuprofen in Single Visit Root Canal Treatment- A Prospective Randomised Pilot Study.
Trial report in European endodontic journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Effect of Pre-emptive Injection-based Corticosteroid Administration and Its Routes on Post-Endodontic Pain: A Systematic Review and Meta-analysis of Randomized Clinical Trials.Journal of clinical and experimental dentistry · 2026Review
- Effect of Submucosal Cryotherapy on Postoperative Pain in Maxillary Premolars with Symptomatic Irreversible Pulpitis: A Prospective, Parallel, Triple-Blinded Randomized Controlled Trial.European journal of dentistry · 2026Article
- Comparative evaluation of pain and bacterial reduction in one-visit and two-visit retreatment of single-rooted teeth: A randomized clinical trial.Journal of conservative dentistry and endodontics · 2025Article
- Effect of Cryotherapy and Occlusal Reduction on Postoperative Endodontic Pain in Mandibular First Molars with Symptomatic Apical Periodontitis: A Prospective, Parallel, Double-Blinded Randomized Controlled Trial.European journal of dentistry · 2025Article
- Assessment of Apical Pressures in Single and Joining Canals - An Ex Vivo Study Based on Computational Fluid Dynamic Analysis.European endodontic journal · 2024Article
- Clinical correlation of salivary alpha-amylase levels with pain intensity in patients undergoing emergency endodontic treatment.BMC oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAdequate pain management is an essential key to success in endodontics. The present study aimed to evaluate the postoperative pain levels and analgesic intake on preemptive versus preventive oral administration of ibuprofen in single visit root canal treatment.
methodsA total of 100 participants presented with symptomatic irreversible pulpitis and with severe baseline pain scores were selected for the study. The participants were randomly allocated into two groups as follows: Group I: preemptive group (n=50), Group II: preventive group (n=50). Participants in group I were administered preoperatively with 600 mg of ibuprofen tablet 1 hour before the procedure, whereas in group II, participants were administered only with a placebo preoperatively. The treatment was finished in a single visit, and 200 mg ibuprofen tablet was administered every eight hours in both groups. The participants were asked to take tablets only when required and evaluated for pain scores and analgesic intake at 6, 24, 48, 72 hour intervals.
resultsThere was a statistically significant decrease (P<0.05) in both the pain levels and tablet intake in the preemptive group compared to the preventive group at 6, 24, 48 and 72 hours. Preemptive group was beneficial in reducing postoperative pain scores and analgesic intake at all time intervals.
conclusionPreemptive analgesic administration seems beneficial in reducing postoperative pain levels and analgesic intake in single visit root canal treatment.
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