ReviewPediatric pulmonology2022
Pulmonary function of children with tracheomalacia and associated clinical factors.
Review in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Respiratory findings and growth parameters in pediatric patients with airway Malacia.European journal of pediatrics · 2026Article
- Diagnosis, Treatment, and Follow-Up of Tracheo/Bronchomalacia in Children: The Italian Multicenter Experience.Children (Basel, Switzerland) · 2025Article
- Oscillometry Phenotypes in Children With Down Syndrome.Pediatric pulmonology · 2025Article
- Role of Spirometry, Radiology, and Flexible Bronchoscopy in Assessing Chronic Cough in Children.Journal of clinical medicine · 2024Review
- Influence of Achalasia on the Spirometry Flow-Volume Curve and Peak Expiratory Flow.Diagnostics (Basel, Switzerland) · 2024Article
- Multidisciplinary approach to vascular rings and vascular-related aerodigestive compression: a clinical practice review.Translational pediatrics · 2023Review
- Pulmonary function of children with tracheomalacia and associated clinical factors.Pediatric pulmonology · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSpirometry is easily accessible yet there is limited data in children with tracheomalacia. Availability of such data may inform clinical practice. We aimed to describe spirometry indices of children with tracheomalacia, including Empey index and flow-volume curve pattern, and determine whether these indices relate with bronchoscopic features.
methodsFrom the database of children with tracheomalacia diagnosed during 2016-2019, we reviewed their flexible bronchoscopy and spirometry data in a blinded manner. We specially evaluated several spirometry indices and tracheomalacia features (cross-sectional lumen reduction, malacic length, and presence of bronchomalacia) and determined their association using multivariable regression.
resultsOf 53 children with tracheomalacia, the mean (SD) peak expiratory flow (PEF) was below the normal range [68.9 percent of predicted value (23.08)]. However, all other spirometry parameters were within normal range [Z-score forced expired volume in 1 s (FEV
conclusionThe "knee" pattern in spirometry flow-volume curve is common in children with tracheomalacia but other indices, including Empey index, cannot be used to characterize tracheomalacia. Spirometry indices were not significantly associated with bronchoscopic tracheomalacia features but children with tracheobronchomalacia have significantly lower flow than those with tracheomalacia alone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.