Evidence map›Paper›PMID 35785442›Full record

Observational studySkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2022

Facial skin characteristics and concerns in Indonesia: A cross-sectional observational study.

Yaping Du, Chandraprabha Doraiswamy, Jie Mao, Qian Zhang, Yan Liang, Zheng Du, Renuka Vasantharaghavan, Manoj Kumar Joshi

2 registry-linked trialsOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05670977 nacompletednot on this mapstarted 2023, after this paper: background citation

A Randomized, Double Blind, Controlled Study of Improved Skin Anti-aging Outcomes Associated With Collagen Fortified Consumption In 30 to 50-Year-old Women

TypeinterventionalSponsorGuangdong HuaPeptides Biotechnology Co., Ltd.Ran2023 to 2023Enrolled70ConditionsSkin Laxity, Skin LinesArmsStudy product plus collagen supplement, Study product without collagen supplement
NCT05696938 nacompletednot on this mapstarted 2023, after this paper: background citation

Improved Skin Whitening Outcomes Associated With Nicotinamide Fortified Consumption in 30 to 50-Year-old Women, a Double Blind, Control and Randomized Study

TypeinterventionalSponsorShenzhen Precision Health Food Technology Co. Ltd.,Ran2023 to 2023Enrolled70ConditionsSkin DarkenArmsWonderlab Nicotinamide Drink, Ordinary Drink
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. [Physiological Characteristics of the Facial Skin in Ethnic Tibetan Population Living at High Altitudes].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  5. Relationship Between Facial Melasma and Ocular Photoaging Diseases.Medical sciences (Basel, Switzerland) · 2025
    Article
  6. Skinly: A novel handheld IoT device for validating biophysical skin characteristics.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  7. Article
  8. Annals of dermatology · 2023
    Article
  9. Facial skin characteristics and concerns in Indonesia: A cross-sectional observational study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yaping DuUnilever R&D Shanghai, Shanghai, China.
Chandraprabha DoraiswamyUnilever R&D Bangalore, Bangalore, India.
Jie MaoUnilever R&D Shanghai, Shanghai, China.
Qian ZhangUnilever R&D Shanghai, Shanghai, China.
Yan LiangUnilever R&D Shanghai, Shanghai, China.
Zheng DuUnilever R&D Shanghai, Shanghai, China.
Renuka VasantharaghavanUnilever R&D Bangalore, Bangalore, India.
Manoj Kumar JoshiUnilever R&D Bangalore, Bangalore, India.ORCID https://orcid.org/0000-0002-7725-125X
Unilever (China) · CNUnilever (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFacial skin characteristics and appearance vary according to ethnicity. While much of this knowledge is derived from the Caucasian population, lately there have been efforts to gain such understanding in various regions in Asia.  In this paper, we have built an understanding of such features in Indonesia. In Indonesia, a section of females wears a traditional veil (hijab) to cover the scalp and part of face. The influence of the hijab on facial skin attributes was also investigated.

methodsIn a cross-sectional observational study design involving 419 female volunteers in Jakarta, Indonesia, facial skin attributes (colour, radiance, hydration, trans-epidermal water loss [TEWL], wrinkles, fine lines, pores, and sebum levels) and conditions (melasma, post-inflammatory hyperpigmentation (PIH), solar lentigines/ senile lentigines, seborrheic keratoses and acne) were assessed by trained operators and dermatologists using standard validated instruments and scales.

resultsWith age, facial skin colour showed darkening in cheek; forehead on the other hand showed slight lightening. The skin evenness and radiance decreased, substantially. Aging attributes measured in terms of lines, wrinkles, and under-eye dark circles showed deterioration with age; the decline was progressively faster than colour change. Facial image data analysis corroborated these findings. Skin hydration remained similar across the age groups even though the skin barrier function measured in terms of TEWL improved with age. Sebum levels in the skin were similar up to the age of 50 but declined in the next group of 50-60 year. Pore severity increased with age. Melasma, seborrheic keratosis and PIH showed a high prevalence (>∼50%) at the young age group (20-30 years), itself. Melasma prevalence attained 100% in the age group of 41-50 year and onwards, and its severity similarly showed a steady rise with age. PIH on the other hand showed a steady decline with age. Solar lentigines prevalence (∼30%) did not change much across age groups, and the severity scores were similar in age groups up to 50 year but increased substantially in 51-60-year age groups. Seborrheic keratosis was similar (∼47%) in age groups up 20-40 year but steadily increased in upper age groups. Its severity was similar in the age groups of 20-30 year and 31-40 year but showed a two-fold increase in subsequent age groups. Acne was 10% in the age group of 20-30 year and declined gradually to 0.7% in the 51-60-year age group. Hijab wearers showed slight protection in skin colour darkening and improvement of evenness and radiance but were similar on aging (fine lines and wrinkles on crow's feet, under eye and peri-oral areas) markers to non-wearers. In general, in majority of age-groups, hijab wearers showed a higher prevalence of melasma, solar/senile lentigines, seborrheic keratosis and PIH.

Indexed as

Acne VulgarisHyperpigmentationKeratosis, SeborrheicLentigoMelanosisSkin AgingAdultCross-Sectional StudiesFemaleHumansIndonesiaMiddle AgedWaterYoung AdultWateragingethnicityfacial skin attributesskin conditions

Identifiers

PMID35785442
PMCPMC9907585
OpenAlexW4283792283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.