ArticleMetabolism open2022
Evaluation of
Article in Metabolism open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Phytochemical profiling and antidiarrheal activity of Sophora japonica L. fruit extract.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Article
- Evaluation of the Antidiarrheal Activity of 80% Methanolic Extract and Solvent Fractions of Calpurnia aurea (Ait.) Benth. (Fabaceae) Roots in Swiss Albino Mice.BioMed research international · 2026Article
- Article
- Sustainable Utilization of Agricultural By-Products:Journal of pharmacopuncture · 2025Article
- Evaluation of anti-ulcer activity of hydromethanol crude extract and solvent fractions of Vicia faba (Fabaceae) seeds in mice.PloS one · 2025Article
- Article
- DecipheringAdvances in pharmacological and pharmaceutical sciences · 2024Article
- Review of Medicinal Plants Traditionally Used to Treat Diarrhea by the People in the Amhara Region of Ethiopia.Evidence-based complementary and alternative medicine : eCAM · 2023Review
- Antidiarrheal Activities of the Methanol Leaf Extracts ofJournal of experimental pharmacology · 2023Article
- Evaluation of Anti-Diarrheal Activities of the 80% Methanol Extract and Solvent Fractions ofJournal of experimental pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Natural products have been utilized by human beings for thousands of years to relieve a variety of ailments, including diarrhea. Conventional antidiarrheal drugs are associated with multiple adverse effects and contraindications. Traditionally, Methods: The hydro-methanolic extract was extracted through a cold maceration technique using 80% methanol. Castor oil-induced diarrheal, gastro-intestinal transit, and enteropooling models have been employed to assess the antidiarrheal activity of the test extract at doses of 100, 200, and 400 mg/kg. Results: The crude root extract caused no mortality at a single limit test dose of 2 g/kg throughout the first 24 h and for the rest of the 14 days. In a castor oil-induced diarrheal model, the hydro-methanolic extract markedly delayed the onset of diarrhea, reduced the weight of wet and total feces at 100 ( Conclusion: The study speculated that
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.