Evidence map›Paper›PMID 35784731›Full record

ArticleFrontiers in pharmacology2022

DA-9805, a Herbal Mixture, Restores Motor Manifestations in 6-Hydroxydopamine-induced Parkinson's Disease Mouse Model by Regulating Striatal Dopamine and Acetylcholine Levels.

Eugene Huh, Youngji Kwon, Jin Gyu Choi, Myung Gyu Lim, Jin Seok Jeong, Ah Yeon Park, Jeong Hee Kim, Youngmi Kim Pak, Seon-Pyo Hong, Myung Sook Oh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Apoptosis signal-regulating kinase 1 (Frontiers in cellular neuroscience · 2024
    Article
  5. Bioactive strawberry fruit (Frontiers in neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Eugene HuhDepartment of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Youngji KwonDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, South Korea.
Jin Gyu ChoiDepartment of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Myung Gyu LimDepartment of Oriental Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, South Korea.
Jin Seok JeongR&D Center of Dong-A ST, Yong-in, South Korea.
Ah Yeon ParkR&D Center of Dong-A ST, Yong-in, South Korea.
Jeong Hee KimDepartment of Life and Nanopharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, South Korea.
Youngmi Kim PakMedical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute, Department of Physiology, College of Medicine, Kyung Hee University, Seoul, South Korea.
Seon-Pyo HongDepartment of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Myung Sook OhDepartment of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul, South Korea.
Kyung Hee University · KRDong-A ST (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loss of dopamine (DA) is one of the primary features of Parkinson's disease (PD); however, imbalances of non-dopaminergic neurotransmitters significantly contribute to the disabilities noted in advanced PD patients. DA-9805 is the ethanolic extraction of the root bark of

Indexed as

acetylcholineDA-9805dopaminehomeostasisParkinson’s diseasestriatal neurotransmission

Identifiers

PMID35784731
PMCPMC9240257
OpenAlexW4282913135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.