Evidence map›Paper›PMID 35784725›Full record

ArticleFrontiers in pharmacology2022

Therapeutic Efficacy of Carvacrol-Loaded Nanoemulsion in a Mouse Model of Schistosomiasis.

Edilaine S Xavier, Rafael L de Souza, Vinícius C Rodrigues, Camila O Melo, Daniel B Roquini, Bruna L Lemes, Polrat Wilairatana, Elquio E Oliveira, Josué de Moraes

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Plant-Derived Terpenes as Emerging Therapeutics Against Schistosomiasis.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Edilaine S XavierResearch Center for Neglected Diseases, Guarulhos University, Guarulhos, Brazil.
Rafael L de SouzaLaboratory of Synthesis and Drug Delivery, State University of Paraiba, João Pessoa, Brazil.
Vinícius C RodriguesResearch Center for Neglected Diseases, Guarulhos University, Guarulhos, Brazil.
Camila O MeloLaboratory of Synthesis and Drug Delivery, State University of Paraiba, João Pessoa, Brazil.
Daniel B RoquiniResearch Center for Neglected Diseases, Guarulhos University, Guarulhos, Brazil.
Bruna L LemesResearch Center for Neglected Diseases, Guarulhos University, Guarulhos, Brazil.
Polrat WilairatanaDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Elquio E OliveiraLaboratory of Synthesis and Drug Delivery, State University of Paraiba, João Pessoa, Brazil.
Josué de MoraesResearch Center for Neglected Diseases, Guarulhos University, Guarulhos, Brazil.
Guarulhos University · BRUniversidade Estadual da Paraíba · BRMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since praziquantel is the only drug available to treat schistosomiasis, a neglected parasitic disease that affects more than 240 million people worldwide, there is an urgent demand for new antischistosomal agents. Natural compound-loaded nanoparticles have recently emerged as a promising alternative for the treatment of schistosomiasis. Carvacrol is an antimicrobial monoterpene present in the essential oil extracted from several plants, especially oregano (

Indexed as

antischistosomal compoundsdrug deliveryinfectious diseasesnanoemulsionnanotechnologynatural product

Identifiers

PMID35784725
PMCPMC9247328
OpenAlexW4283077737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.