Evidence map›Paper›PMID 35784719›Full record

ArticleFrontiers in pharmacology2022

Allicin Facilitates Airway Surface Liquid Hydration by Activation of CFTR.

Zhuo-Er Qiu, Jian-Bang Xu, Lei Chen, Ze-Xin Huang, Tian-Lun Lei, Zi-Yang Huang, Xiao-Chun Hou, Hai-Long Yang, Qin-Hua Lin, Yun-Xin Zhu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zhuo-Er QiuSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Jian-Bang XuSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Lei ChenSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Ze-Xin HuangSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Tian-Lun LeiSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Zi-Yang HuangSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Xiao-Chun HouSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Hai-Long YangSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Qin-Hua LinSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Yun-Xin ZhuSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Lei ZhaoState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.
Wen-Liang ZhouSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Yi-Lin ZhangSchool of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airway epithelium plays critical roles in regulating airway surface liquid (ASL), the alteration of which causes mucus stasis symptoms. Allicin is a compound released from garlic and harbors the capacity of lung-protection. However, the potential regulatory effects of allicin on airway epithelium remain elusive. This study aimed to investigate the effects of allicin on ion transport across airway epithelium and evaluate its potential as an expectorant. Application of allicin induced Cl

Indexed as

airway epitheliumairway surface liquid (ASL)allicinCFTR (cystic fibrosis transmembrane conductance regulator)Cl− secretion

Identifiers

PMID35784719
PMCPMC9241074
OpenAlexW4282919564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.