Evidence map›Paper›PMID 35784689›Full record

ArticleFrontiers in pharmacology2022

Case Report: Bosentan and Sildenafil Exposure in Human Milk - A Contribution From the ConcePTION Project.

Nina Nauwelaerts, Michael Ceulemans, Neel Deferm, An Eerdekens, Bart Lammens, Yeghig Armoudjian, Kristel Van Calsteren, Karel Allegaert, Loes de Vries, Pieter Annaert and 1 more

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06042803 (Clinical Lactation Study on the Exposure to Medicines Via Human Milk), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06042803 recruitingnot on this mapstarted 2023, after this paper: background citation

Clinical Lactation Study on the Exposure to Medicines Via Human Milk: an Umbrella Study Protocol

TypeobservationalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2023 to 2027Enrolled30ConditionsBreast Feeding, Human MilkArmsHuman milk collection, Optionally: maternal blood sample, Optionally: child blood sample
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Pulmonary Hypertension in Women.Methodist DeBakey cardiovascular journal · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Nina NauwelaertsDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Michael CeulemansDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Neel DefermDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
An EerdekensNeonatal Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium.
Bart LammensBioNotus GCV, Niel, Belgium.
Yeghig ArmoudjianBioNotus GCV, Niel, Belgium.
Kristel Van CalsterenGynaecology and Obstetrics, UZ Leuven, Leuven, Belgium.
Karel AllegaertDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Loes de VriesTeratology Information Service, Netherlands Pharmacovigilance Centre Lareb, 's Hertogenbosch, Netherlands.
Pieter AnnaertDepartment of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Anne SmitsL-C&Y, KU Leuven Child & Youth Institute, Leuven, Belgium.
KU Leuven · BEErasmus MC · NLNetherlands Pharmacovigilance Centre Lareb · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bosentanbreastfeedingcase reporthuman milklactationpharmacokineticspulmonary arterial hypertensionsildenafil

Identifiers

PMID35784689
PMCPMC9240352
OpenAlexW4282936360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.