Evidence map›Paper›PMID 35784663›Full record

ArticleFrontiers in oral health2022

Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid.

Menke J de Smit, Poerwati Soetji Rahajoe, Elisabeth Raveling-Eelsing, Paola Lisotto, Hermie J M Harmsen, Nyoman Kertia, Arjan Vissink, Johanna Westra

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Engineering live attenuated vaccines: Old dogs learning new tricks.Journal of translational autoimmunity · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Menke J de SmitDepartment of Dentistry, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Poerwati Soetji RahajoeDepartment of Oral Surgery, Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Elisabeth Raveling-EelsingDepartment of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Paola LisottoDepartment of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Hermie J M HarmsenDepartment of Medical Microbiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Nyoman KertiaDepartment of Rheumatology, Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Arjan VissinkDepartment of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Johanna WestraDepartment of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
University of Groningen · NLRumah Sakit Umum Pusat Dr. Sardjito · IDUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The relation between rheumatoid arthritis (RA) and periodontitis (PD) has been investigated ever since the discovery of the citrullinating enzyme peptidyl arginine deaminase presents in the oral bacterium Aim: The purpose of this study was to assess whether the subgingival microbiome is related to the presence of IgA ACPA in the GCF of healthy individuals with or without PD. Patients and Methods: Healthy individuals with a known periodontal status and high IgA ACPA (>0.1 U/ml) in GCF ( Results: Between groups with or without PD, or with or without IgA ACPA in GCF, no differences in alpha diversity were seen. Beta diversity was different between groups with or without PD ( Conclusion: Periodontitis and certain taxa, including

Indexed as

anti-citrullinated protein antibodies (ACPA)microbiome and dysbiosismucosal inflammationperiodontitisrheumatoid arthritis

Identifiers

PMID35784663
PMCPMC9243218
OpenAlexW4282983199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.