Evidence map›Paper›PMID 35784649›Full record

ArticleCell reports methods2022

Fast construction of interpretable whole-brain decoders.

Sangil Lee, Eric T Bradlow, Joseph W Kable

Abstract read
In one paragraph

Article in Cell reports methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Distinguishing deception from its confounds by improving the validity of fMRI-based neural prediction.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sangil LeeDepartment of Psychology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Eric T BradlowMarketing Department, Wharton School, University of Pennsylvania, PA 19104, USA.
Joseph W KableDepartment of Psychology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.

Funding

Retraining Neurocognitive Mechanisms of Cancer Risk Behavior (PQ4)R01CA170297 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KABLE, JOSEPH W, LERMAN, CARYN · 2012 to 2015
$2.0M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
NCI NIH HHS R01 CA170297NIH HHS S10 OD023495
6 · The paper itself

Abstract

Researchers often seek to decode mental states from brain activity measured with functional MRI. Rigorous decoding requires the use of formal neural prediction models, which are likely to be the most accurate if they use the whole brain. However, the computational burden and lack of interpretability of off-the-shelf statistical methods can make whole-brain decoding challenging. Here, we propose a method to build whole-brain neural decoders that are both interpretable and computationally efficient. We extend the partial least squares algorithm to build a regularized model with variable selection that offers a unique "fit once, tune later" approach: users need to fit the model only once and can choose the best tuning parameters post hoc. We show in real data that our method scales well with increasing data size and yields interpretable predictors. The algorithm is publicly available in multiple languages in the hope that interpretable whole-brain predictors can be implemented more widely in neuroimaging research.

Indexed as

BrainBrain MappingAlgorithmsMagnetic Resonance ImagingNeuroimagingbig databrain decodingfMRIMVPAprediction

Identifiers

PMID35784649
PMCPMC9243546

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.