ArticleBioactive materials2023
Gold@Halloysite nanotubes-chitin composite hydrogel with antibacterial and hemostatic activity for wound healing.
Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 174 citations in OpenAlex.
- A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Pooled it
- Tunable Fabrication of 2D-Layered Magnesium Nanosilicates With Hemostatic Properties.Small science · 2026Article
- Natural Polymer-Based Hemostatic Hydrogels with Advanced Material and Structural Designs for Functional Applications.Pharmaceutics · 2026Review
- Innovative applications of multidimensional engineered hydrogels in wound healing.Journal of advanced research · 2026Review
- Article
- 3D printing of chitosan hydrogel reinforced with tubular nanoclay for hemostasis and infected wound healing.Bioactive materials · 2025Article
- Injectable and Self-Healing Boronic-Acid-Modified Succinoglycan Hydrogels: Dual-Stimuli-Responsive Platforms for Controlled Tannic Acid Release.Gels (Basel, Switzerland) · 2025Article
- Natural-origin bioadhesive hydrogel with dual antioxidative and immunoregulatory properties for enhanced angiogenesis and wound healing.Bioactive materials · 2025Article
- Strategies and applications of antibacterial surface-modified biomaterials.Bioactive materials · 2025Review
- Molecular Design of a Naturally Derived Hemostatic Sealant with Prolonged Antimicrobial Activity for Repairing Elastic Organ Injuries.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A calcium-copper-based zeolite with dual functions of hemostatic and antibacterial properties.RSC advances · 2025Article
- Mesenchymal stem cells and their exosomes: a novel approach to skin regeneration via signaling pathways activation.Journal of molecular histology · 2025Review
- Green biosynthetic silver nanoparticles fromMaterials today. Bio · 2025Article
- Group IB Metal-Based Nanomaterials for Antibacterial Applications.Small science · 2025Review
- Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing.Bioactive materials · 2025Article
- Role of metal nanomaterials in wound healing - a review.Frontiers in bioengineering and biotechnology · 2025Review
- Engineering natural DNA matrices with halloysite nanotubes to fabricate injectable therapeutic hydrogels for bone regeneration.Journal of orthopaedic translation · 2024Article
- Nanomaterials for Photothermal Antimicrobial Surfaces.ACS omega · 2024Review
- X-ray-activated polymerization expanding the frontiers of deep-tissue hydrogel formation.Nature communications · 2024Article
- Clays and Wound Healing.Materials (Basel, Switzerland) · 2024Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection and healing of wounds after injury has always been an unavoidable problem in daily life, so design of a biomaterial with antibacterial and good wound healing properties is highly needed. Herein, a wound healing hydrogel dressing with halloysite clay and chitin as the main components was prepared, which combines the advantages of the biomacromolecule and clay. Halloysite nanotubes (HNTs) are extremely biocompatible clay materials with a hollow tubular structure, and the inner and outer surfaces of HNTs are composed of SiOx and AlOx layers with different charges. Au nanoparticles with diameter in 5-10 nm were filled into the HNTs' lumen to endow photothermal effect of the clay materials. Au@HNTs was then mixed with chitin solution to prepare flexible composite hydrogel by crosslinking by epichlorohydrin. The antibacterial properties, biocompatibility and hemostatic properties of the hydrogel material were investigated by antibacterial experiments, cell experiments, mouse liver and tail hemostatic experiments. After infecting the back wound of mice with Staphylococcus aureus, the hydrogel was applied to the wound to further verify the killing effect on bacteria and wound healing effect of the hydrogel material in vivo. The Au@HNTs-chitin composite hydrogel exhibits high antibacterial and hemostatic activity as well as promoting wound healing function with low cytotoxicity. This study is significant for the development of high-performance wound dressings based on two commonly used biocompatible materials, which shows promising application in wound sterilization and healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.