Evidence map›Paper›PMID 35784623›Full record

ArticleAnnals of gastroenterology

Safety of endoscopic mucosal resection of large colonic polyps in elderly patients: a systematic review and meta-analysis.

Umair Iqbal, Ahmad Nawaz, Zohaib Ahmed, Faisal Kamal, Wade Lee-Smith, Muhammad Ali Khan, Yasin Alastal, Bradley D Confer, Harshit S Khara

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Umair IqbalDivision of Gastroenterology and Hepatology, Geisinger Medical Center, Pennsylvania (Umair Iqbal, Bradley D.Confer, Harshit S. Khara).
Ahmad NawazDivision of Internal Medicine, Yale-New Haven Hospital, Connecticut (Ahmad Nawaz).
Zohaib AhmedDivision of Internal Medicine, University of Toledo Medical Center, Ohio (Zohaib Ahmed, Wade Lee-Smith, Yasin Alastal).
Faisal KamalDivision of Gastroenterology, University of California, San Francisco, California (Faisal Kamal).
Wade Lee-SmithDivision of Internal Medicine, University of Toledo Medical Center, Ohio (Zohaib Ahmed, Wade Lee-Smith, Yasin Alastal).
Muhammad Ali KhanUniversity of Toledo Libraries, University of Toledo, Toledo, Ohio (Muhammad Ali Khan).
Yasin AlastalDivision of Internal Medicine, University of Toledo Medical Center, Ohio (Zohaib Ahmed, Wade Lee-Smith, Yasin Alastal).
Bradley D ConferDivision of Gastroenterology and Hepatology, Geisinger Medical Center, Pennsylvania (Umair Iqbal, Bradley D.Confer, Harshit S. Khara).
Harshit S KharaDivision of Gastroenterology and Hepatology, Geisinger Medical Center, Pennsylvania (Umair Iqbal, Bradley D.Confer, Harshit S. Khara).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endoscopic mucosal resection (EMR) is a procedure commonly used for large sessile and flat polyps. However, it may cause bleeding, perforation, and complications related to anesthesia. There are limited data on the safety and efficacy of EMR in the elderly. Therefore, we conducted a comprehensive review and meta-analysis to assess EMR safety in elderly patients. Methods: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Web of Science Core Collection for studies evaluating EMR for large colorectal lesions (>20 mm) in older patients (75+ years). Our primary result was post-polypectomy bleeding and perforation, while our secondary outcome was recurrence or residual polyp. Results: The meta-analysis included 6 studies with 2903 patients. The rate of post-polypectomy bleeding was 5.3% (95% confidence interval [CI] 2.3-11.7%), Conclusion: EMR is as safe for the elderly as it is for younger patients, and is not associated with a greater risk of bleeding or perforation.

Indexed as

Colorectal cancerelderlyendoscopic mucosal resectionpolypectomy

Identifiers

PMID35784623
PMCPMC9210775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.