Evidence map›Paper›PMID 35784593›Full record

ArticleThe Pan African medical journal2022

The out-of-pocket cost of breast cancer care at a public tertiary care hospital in Nigeria: an exploratory analysis.

Gregory Christopher Knapp, Funmilola Olanike Wuraola, Olalekan Olasehinde, Anya Romanoff, Peter Thomas Kingham, Olusegun Isaac Alatise

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06630962 (Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06630962 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care: A Randomized Control Trial- COST-FIN

TypeinterventionalSponsorNorthwestern UniversityRan2024 to 2026Enrolled200ConditionsBreast Neoplasm, Prostate Neoplasm, Colon Neoplasm, Rectal NeoplasmArmsFinancial Navigation Program
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Evaluation of financial toxicity and associated factors in female patients with breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  4. Constructing the scale to measure financial toxicity in cancer patients for Low-middle income countries (FT-LM) by using the modified Delphi method.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gregory Christopher KnappDepartment of Surgery, Division of General Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
Funmilola Olanike WuraolaDepartment of Surgery, College of Health Sciences, Obafemi Awolowo University (OAU), Ile-Ife, Nigeria.
Olalekan OlasehindeDepartment of Surgery, College of Health Sciences, Obafemi Awolowo University (OAU), Ile-Ife, Nigeria.
Anya RomanoffMemorial Sloan Kettering Cancer Center, New York, New York, United States of America.
Peter Thomas KinghamMemorial Sloan Kettering Cancer Center, New York, New York, United States of America.
Olusegun Isaac AlatiseDepartment of Surgery, College of Health Sciences, Obafemi Awolowo University (OAU), Ile-Ife, Nigeria.
Memorial Sloan Kettering Cancer Center · USDalhousie University · CA

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Introduction: in Nigeria, the incidence of breast cancer has increased by over 80% in the last four decades. This study quantifies the out-of-pocket (OOP) cost of breast cancer management and the associated rate of catastrophic healthcare expenditure (CHE) at a public tertiary care facility in Ile-Ife, Nigeria. Methods: patients treated between December 2017 - August 2018 were identified from a prospective breast cancer database. A questionnaire was developed to capture the total cost of care, including direct and indirect expenses. Three commonly used thresholds for a CHE were used in this analysis. The cost of radiotherapy and targeted therapy were captured separately. Results: data was collected from 22 eligible patients. Sixty-eight percent had no form of health insurance. The mean cost of diagnosis and treatment was $2,049 (SD $1,854). At a threshold of 10% and 25% of annual income, 95% and 86% of households experienced a CHE. Based on a household´s capacity-to-pay, 90% experienced a CHE. The mean cost of radiotherapy was $462 (SD $223) and the mean cost of trastuzumab was $6,568 (SD $2,766). Cost precluded surgery in 14% of patients with resectable disease. As a result of accessing treatment, 72% of households had to borrow money and 9% of households interrupted a child´s education. Conclusion: the out-of-pocket cost of breast cancer care in Nigeria is significant. This results in a CHE for 68-95% of households, which has significant health and economic sequelae. Greater financial protection is essential as the burden of breast cancer increases in Nigeria.

Indexed as

Breast NeoplasmsChildFemaleHealth ExpendituresHumansNigeriaProspective StudiesTertiary Care Centersbreast cancerfinancial toxicityNigeriaOut-of-pocket cost

Identifiers

PMID35784593
PMCPMC9206173
OpenAlexW4226171086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.