Evidence map›Paper›PMID 35784317›Full record

ArticleFrontiers in immunology2022

Murine Q Fever Vaccination Model Reveals Sex Dimorphism in Early Phase Delayed-Type Hypersensitivity Responses.

Picabo Binette, Mahelat Tesfamariam, Diane Cockrell, Robert A Heinzen, Crystal Richards, Carl Shaia, Carrie Mae Long

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Characterization ofMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Picabo BinetteLaboratory of Bacteriology, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
Mahelat TesfamariamLaboratory of Bacteriology, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
Diane CockrellLaboratory of Bacteriology, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
Robert A HeinzenLaboratory of Bacteriology, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
Crystal RichardsLaboratory of Bacteriology, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
Carl ShaiaRocky Mountain Veterinary Branch, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
Carrie Mae LongLaboratory of Bacteriology, Intramural Research Program, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, United States.
National Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

Genetics of Coxiella burnetiiZIAAI000946 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HEINZEN, ROBERT A · 2009 to 2023
$8.9M
Coxiella burnetii immunobiology, host-pathogen modeling, and countermeasure development ZIAAI001331 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LONG, CARRIE MAE · 2020 to 2025
$6.5M
Intramural NIH HHS ZIA AI001331
6 · The paper itself

Abstract

Delayed-type hypersensitivity (DTH) responses to microbial vaccines and related components are a major roadblock for widespread licensing of whole cell vaccines such as that of Q fever. Q fever is a zoonotic disease caused by the intracellular bacterium

Indexed as

Coxiella burnetiiQ FeverAnimalsBacterial VaccinesFemaleMaleMiceSex CharacteristicsVaccinationBacterial Vaccinesbacterial vaccineCoxiella burnetiiDTH (delayed type hypersensitivity)Q fever Vaccine (Q-VAX®)sex dimorphismvaccine allergy

Identifiers

PMID35784317
PMCPMC9241443
OpenAlexW4282974896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.