Evidence map›Paper›PMID 35784292›Full record

ArticleFrontiers in immunology2022

Virus-Like Particles Are Efficient Tools for Boosting mRNA-Induced Antibodies.

Anne-Cathrine S Vogt, Lukas Jörg, Byron Martina, Pascal S Krenger, Xinyue Chang, Andris Zeltins, Monique Vogel, Mona O Mohsen, Martin F Bachmann

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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  7. Cancer/Testis Antigens as Targets for RNA-Based Anticancer Therapy.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Anne-Cathrine S VogtDepartment of Rheumatology and Immunology, University Hospital, Bern, Switzerland.
Lukas JörgDivision of Allergology and Clinical Immunology, Department of Pneumology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Byron MartinaErasmus Medical Center, Department of Viroscience, Rotterdam, Netherlands.
Pascal S KrengerDepartment of Rheumatology and Immunology, University Hospital, Bern, Switzerland.
Xinyue ChangDepartment of Rheumatology and Immunology, University Hospital, Bern, Switzerland.
Andris ZeltinsLatvian Biomedical Research & Study Centre, Riga, Latvia.
Monique VogelDepartment of Rheumatology and Immunology, University Hospital, Bern, Switzerland.
Mona O MohsenDepartment of Rheumatology and Immunology, University Hospital, Bern, Switzerland.
Martin F BachmannDepartment of Rheumatology and Immunology, University Hospital, Bern, Switzerland.
University Hospital of Bern · CHUniversity of Bern · CHLatvian Biomedical Research and Study Centre · LVUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

mRNA based vaccines against COVID-19 have proven most successful at keeping SARS-CoV-2 pandemic at bay in many countries. Recently, there is an increased interest in heterologous prime-boost vaccination strategies for COVID-19 to maintain antibody responses for the control of continuously emerging SARS-CoV-2 variants of concern (VoCs) and to overcome other obstacles such as supply shortage, costs and reduced safety issues or inadequatly induced immune-responses. In this study, we investigated the antibody responses induced by heterologous prime-boost with vaccines based on mRNA and virus-like particles (VLPs). The VLP-based mCuMV

Indexed as

COVID-19SARS-CoV-22019-nCoV Vaccine mRNA-1273COVID-19 VaccinesHumansImmunoglobulin GRNA, Messenger2019-nCoV Vaccine mRNA-1273COVID-19 VaccinesImmunoglobulin GRNA, MessengerCOVID-19mRNASARS-CoV-2vaccinevirus-like particles

Identifiers

PMID35784292
PMCPMC9245429
OpenAlexW4283025443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.