ArticleNeuroimage. Reports2022
Selective vulnerability of medial temporal regions to short-term blood pressure variability and cerebral hypoperfusion in older adults.
Article in Neuroimage. Reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 20 citations in OpenAlex.
- 24-Hour Blood Pressure Variability Via Ambulatory Monitoring and Risk for Probable Dementia in the SPRINT Trial.The journal of prevention of Alzheimer's disease · 2024Trial
- Blood Pressure Variability and Cerebral Perfusion Decline: A Post Hoc Analysis of the SPRINT MIND Trial.Journal of the American Heart Association · 2023Trial
- Blood Pressure Variability and Cognitive Decline: A Post Hoc Analysis of the SPRINT MIND Trial.American journal of hypertension · 2023Trial
- Lower cardiac output is a risk factor for faster cerebral atrophy over a 11-year follow-up period in APOE-ε4 carriers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Metabolic parameter variability, brain structure, perfusion, and cognition: a population-based study.Alzheimer's research & therapy · 2026Article
- High systolic blood pressure variability is associated with impaired cerebral autoregulation and poor functional recovery after intracerebral hemorrhage.Scientific reports · 2026Article
- Beat-to-beat blood pressure variability, hippocampal atrophy, and memory impairment in older adults.GeroScience · 2025Article
- Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Hypertension and cerebral blood flow in the development of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Older adults with reduced cerebrovascular reactivity exhibit high white matter hyperintensity burden.Neurobiology of aging · 2024Article
- Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits.medRxiv : the preprint server for health sciences · 2024Article
- Short-term blood pressure variability and brain functional network connectivity in older adults.Neuroimage. Reports · 2024Article
- Under pressure: A systematic review of the association between blood pressure variability with depression and anxiety.Cerebral circulation - cognition and behavior · 2024Article
- Blood Pressure Variability and Plasma Alzheimer's Disease Biomarkers in the SPRINT Trial.Journal of Alzheimer's disease : JAD · 2024Article
- Blood pressure variability, central autonomic network dysfunction and cerebral small vessel disease in APOE4 carriers.medRxiv : the preprint server for health sciences · 2023Article
- Older Adults With Higher Blood Pressure Variability Exhibit Cerebrovascular Reactivity Deficits.American journal of hypertension · 2023Article
- Short-term blood pressure variability is inversely related to regional amplitude of low frequency fluctuations in older and younger adults.Aging brain · 2023Article
- Blood pressure variability and plasma Alzheimer's disease biomarkers in older adults.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
Abstract
Blood pressure variability is an emerging risk factor for stroke, cognitive impairment, and dementia, possibly through links with cerebral hypoperfusion. Recent evidence suggests visit-to-visit (e.g., over months, years) blood pressure variability is related to cerebral perfusion decline in brain regions vulnerable to Alzheimer's disease. However, less is known about relationships between short-term (e.g., < 24 hours) blood pressure variability and regional cerebral perfusion, and whether these relationships may differ by age. We investigated short-term blood pressure variability and concurrent regional cerebral microvascular perfusion in a sample of community-dwelling older adults without history of dementia or stroke and healthy younger adults. Blood pressure was collected continuously during perfusion MRI. Cerebral blood flow was determined for several brain regions implicated in cerebrovascular dysfunction in Alzheimer's disease. Elevated systolic blood pressure variability was related to lower levels of concurrent cerebral perfusion in medial temporal regions: hippocampus (β = -.60 [95% CI -.90, -.30];
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.