Evidence map›Paper›PMID 35783900›Full record

ArticleHepatology forum2021

Artificial intelligence method to predict overall survival of hepatocellular carcinoma.

Cem Simsek, Deniz Can Guven, Taha Koray Sahin, Ibrahim Emir Tekin, Ozlem Sahan, Hatice Yasemin Balaban, Suayib Yalcin

Open access · bronzeAbstract read
In one paragraph

Article in Hepatology forum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Harnessing the Power of AI for Enhanced Diagnosis and Treatment of Hepatocellular Carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cem SimsekDepartment of Gastroenterology, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-7037-5233
Deniz Can GuvenDepartment of Medical Oncology, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-6924-9467
Taha Koray SahinDepartment of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-3590-0426
Ibrahim Emir TekinDepartment of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0003-4118-8639
Ozlem SahanDepartment of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-0684-8585
Hatice Yasemin BalabanDepartment of Gastroenterology, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-0901-9192
Suayib YalcinDepartment of Medical Oncology, Hacettepe University School of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0001-7850-6798
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Hepatocellular carcinoma (HCC) is a complex disease with heterogenous outcomes influenced by disease- and patient-related factors. The prediction of outcomes requires a comprehensive approach, and artificial intelligence could provide a feasible means of estimating HCC outcomes. This study was designed to assess the viability of a machine learning model to predict survival in HCC patients. Materials and Methods: HCC patient data with at least 5 years of follow-up were retrospectively reviewed. Patients with accessible data on the primary liver disease, tumor and laboratory values at the time of diagnosis, and length of survival were included. A gradient boosting machine learning algorithm was constructed to predict patient survival at 6 time points. Results: A total of 100 HCC patients (80% male) with a median overall survival of 43 months (range: 0.7-256 months) were included. The survival rate for 6, 12, 24, 36, 60, and 120 months was 88%, 81%, 67%, 60%, 40%, and 11%, respectively. The mean area under the curve of the model prediction was 0.92 (0.061) for >6 months, 0.81 (0.107) for >1 year, 0.78 (0.11) for >2 years, 0.81 (0.083) for >3 years, 0.82 (0.079) for >5 years, 0.81 (0.96) for >8 years, and 0.66 (0.14) for >10 years. Conclusion: The machine learning model successfully predicted short- and long-term survival of patients with HCC.

Indexed as

Artificial intelligencehepatocellular carcinomasurvival

Identifiers

PMID35783900
PMCPMC9138921
OpenAlexW3164487157

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.