Evidence map›Paper›PMID 35783623›Full record

ArticleFrontiers in medicine2022

Three-Dimensional Multi-Task Deep Learning Model to Detect Glaucomatous Optic Neuropathy and Myopic Features From Optical Coherence Tomography Scans: A Retrospective Multi-Centre Study.

An Ran Ran, Xi Wang, Poemen P Chan, Noel C Chan, Wilson Yip, Alvin L Young, Mandy O M Wong, Hon-Wah Yung, Robert T Chang, Suria S Mannil and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Diagnostic accuracy of image-based deep learning for glaucomatous optic neuropathy detection: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Artificial Intelligence for Optical Coherence Tomography in Glaucoma.Translational vision science & technology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Deep learning in optical coherence tomography: Where are the gaps?Clinical & experimental ophthalmology · 2023
    Review
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 4 countries.

An Ran RanDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Xi WangDepartment of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Poemen P ChanDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Noel C ChanDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Wilson YipDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Alvin L YoungDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Mandy O M WongDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Hon-Wah YungTuen Mun Eye Centre, Hong Kong, Hong Kong SAR, China.
Robert T ChangDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, United States.
Suria S MannilDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA, United States.
Yih Chung ThamSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Ching-Yu ChengSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Hao ChenDepartment of Computer Science and Engineering, The Hong Kong University of Science and Technology, Hong Kong, Hong Kong SAR, China.
Fei LiState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China.
Xiulan ZhangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China.
Pheng-Ann HengDepartment of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Clement C ThamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Carol Y CheungDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Chinese University of Hong Kong · HKNational University of Singapore · SGSmith-Kettlewell Eye Research Institute · USSun Yat-sen University · CNHong Kong University of Science and Technology · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aim to develop a multi-task three-dimensional (3D) deep learning (DL) model to detect glaucomatous optic neuropathy (GON) and myopic features (MF) simultaneously from spectral-domain optical coherence tomography (SDOCT) volumetric scans. Methods: Each volumetric scan was labelled as GON according to the criteria of retinal nerve fibre layer (RNFL) thinning, with a structural defect that correlated in position with the visual field defect (i.e., reference standard). MF were graded by the SDOCT Results: A total of 8,151 SDOCT volumetric scans from 3,609 eyes were collected. For detecting GON, in the internal validation, the proposed 3D model had significantly higher AUROC (0.949 vs. 0.913, Conclusion: The proposed multi-task 3D DL model demonstrated high generalizability in all the datasets and the presence of MF did not affect the accuracy of GON detection generally.

Indexed as

artificial intelligencedeep learningglaucomaglaucomatous optic neuropathymulti-taskmyopiamyopic featuresoptical coherence tomography

Identifiers

PMID35783623
PMCPMC9240220
OpenAlexW4282945766

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.