Evidence map›Paper›PMID 35783418›Full record

ArticleFrontiers in microbiology2022

Intestinal Microbes in Patients With Schizophrenia Undergoing Short-Term Treatment: Core Species Identification Based on Co-Occurrence Networks and Regression Analysis.

Min Xiang, Liqin Zheng, Daoshen Pu, Feng Lin, Xiaodong Ma, Huiqian Ye, Daoqiong Pu, Ying Zhang, Dong Wang, Xiaoli Wang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Min XiangMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.
Liqin ZhengMOE Key Lab for Neuroinformation, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu, China.
Daoshen PuThe Fourth People's Hospital of Ya'an, Ya'an, China.
Feng LinMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.
Xiaodong MaMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.
Huiqian YeMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.
Daoqiong PuMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.
Ying ZhangMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.
Dong WangPsychiatry Department, The Fourth People's Hospital of Ya'an, Ya'an, China.
Xiaoli WangInternal Medicine, The Fourth People's Hospital of Ya'an, Ya'an, China.
Kaiqing ZouThe Outpatient Department, The Fourth People's Hospital of Ya'an, Ya'an, China.
Linqi ChenMOE Key Lab for Neuroinformation, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu, China.
Yong ZhangMOE Key Lab for Neuroinformation, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu, China.
Zhanjiang SunMOE Key Lab for Neuroinformation, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu, China.
Tao ZhangMOE Key Lab for Neuroinformation, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu, China.
Guolin WuMedical Laboratory, The Fourth People's Hospital of Ya'an, Ya'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia, a common mental disorder, has a tremendous impact on the health and economy of people worldwide. Evidence suggests that the microbial-gut-brain axis is an important pathway for the interaction between the gut microbiome and the development of schizophrenia. What is not clear is how changes in the gut microbiota composition and structure during antipsychotic treatment improve the symptoms of schizophrenia. In this study, 25 patients with schizophrenia were recruited. Their fecal samples were collected before and after hospital treatment for 14-19 days. The composition and structure of the intestinal microbiota were evaluated by 16S rRNA sequencing analysis, and the results showed significant differences in fecal microbiota before and after treatment.

Indexed as

16S rRNA sequencingfecal microbiota transplantationgut-brain axisgut microbiotaschizophrenia

Identifiers

PMID35783418
PMCPMC9247572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.