Evidence map›Paper›PMID 35783361›Full record

ArticleFrontiers in virology (Lausanne, Switzerland)2022

Molecular Biology and Diversification of Human Retroviruses.

Morgan E Meissner, Nathaniel Talledge, Louis M Mansky

Open access · goldAbstract read
In one paragraph

Article in Frontiers in virology (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Virotherapy as Gene Deliver for Anti-Cancer Therapy: A Review Article.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Morgan E MeissnerInstitute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455 USA.
Nathaniel TalledgeInstitute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455 USA.
Louis M ManskyInstitute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN 55455 USA.
Twin Cities Orthopedics · USUniversity of Minnesota · US

Funding

Training in PharmacoNeuroImmune Substance Abuse ResearchT32DA007097 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI MOLITOR, THOMAS WILLIAM · 1985 to 2021
$13.1M
Minnesota Training Program in VirologyT32AI083196 · NIAID · UNIVERSITY OF MINNESOTA · PI Louis M Mansky · 2010 to 2026
$3.2M
HIV Gag lattice morphology and particle biogenesisR01AI150468 · NIAID · UNIVERSITY OF MINNESOTA · PI MANSKY, LOUIS M., MUELLER, JOACHIM D · 2019 to 2020
$1.2M
Molecular Determinants of Retroviral Capsid Morphology using a Novel Imaging ApproachF32AI150351 · NIAID · UNIVERSITY OF MINNESOTA · PI TALLEDGE, NATHANIEL LEE · 2020 to 2021
$141k
Cellular determinants of HIV mutagenesisF31AI150487 · NIAID · UNIVERSITY OF MINNESOTA · PI MEISSNER, MORGAN · 2020 to 2020
$39k
NIAID NIH HHS F31 AI150487NIAID NIH HHS F32 AI150351NIAID NIH HHS R01 AI150468NIAID NIH HHS T32 AI083196NIDA NIH HHS T32 DA007097
6 · The paper itself

Abstract

Studies of retroviruses have led to many extraordinary discoveries that have advanced our understanding of not only human diseases, but also molecular biology as a whole. The most recognizable human retrovirus, human immunodeficiency virus type 1 (HIV-1), is the causative agent of the global AIDS epidemic and has been extensively studied. Other human retroviruses, such as human immunodeficiency virus type 2 (HIV-2) and human T-cell leukemia virus type 1 (HTLV-1), have received less attention, and many of the assumptions about the replication and biology of these viruses are based on knowledge of HIV-1. Existing comparative studies on human retroviruses, however, have revealed that key differences between these viruses exist that affect evolution, diversification, and potentially pathogenicity. In this review, we examine current insights on disparities in the replication of pathogenic human retroviruses, with a particular focus on the determinants of structural and genetic diversity amongst HIVs and HTLV.

Indexed as

diversificationhuman immunodeficiency virushuman T-cell leukemia virusmolecular biologyretrovirus

Identifiers

PMID35783361
PMCPMC9242851
OpenAlexW4281681754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.