Evidence map›Paper›PMID 35783300›Full record

ArticleFrontiers in pediatrics2022

Small Airway Dysfunction Measured by Impulse Oscillometry and Fractional Exhaled Nitric Oxide Is Associated With Asthma Control in Children.

Liang-Mei Lin, Yu-Jun Chang, Kuender D Yang, Ching-Hsiung Lin, Jien-Wen Chien, Jun-Kai Kao, Ming-Sheng Lee, Tsay-I Chiang, Ching-Yuang Lin, Yi-Giien Tsai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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  8. Long-term PMERJ open research · 2025
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  9. Review
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  12. Long-term PMPediatric research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Liang-Mei LinRespiratory Therapy Section for Children, Changhua Christian Children's Hospital, Changhua, Taiwan.
Yu-Jun ChangEpidemiology and Biostatistics Center and Big Data Center, Changhua Christian Hospital, Changhua, Taiwan.
Kuender D YangDepartments of Pediatrics, Mackay Memorial Hospital, Taipei City, Taiwan.
Ching-Hsiung LinDivision of Chest Medicine, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Jien-Wen ChienDepartment of Pediatrics, Changhua Christian Children's Hospital, Changhua, Taiwan.
Jun-Kai KaoDepartment of Pediatrics, Changhua Christian Children's Hospital, Changhua, Taiwan.
Ming-Sheng LeeDepartment of Pediatrics, Changhua Christian Children's Hospital, Changhua, Taiwan.
Tsay-I ChiangCollege of Nursing, Hungkuang University, Taichung, Taiwan.
Ching-Yuang LinDivision of Pediatric Nephrology, Children's Hospital, China Medical University, Taichung, Taiwan.
Yi-Giien TsaiDepartment of Pediatrics, Changhua Christian Children's Hospital, Changhua, Taiwan.
Changhua Christian Hospital · TWNational Chung Hsing University · TWChina Medical University · TWHungkuang University · TWMackay Memorial Hospital · TWMingDao University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Impulse oscillometry (IOS) and fractional exhaled nitric oxide (FeNO) are sensitive and non-invasive methods to measure airway resistance and inflammation, although there are limited population-based studies using IOS and FeNO to predict asthma control. Objective: This study aimed to investigate the utility of IOS and FeNO for assessing childhood asthma control in terms of small airway dysfunction and airway inflammation. Methods: This prospective observational cohort study enrolled 5,018 school children (aged 6-12 years), including 560 asthmatic children and 140 normal participants. FeNO, spirometry, IOS, bronchial dilation test, total IgE, and childhood asthma control test (C-ACT) were measured. FeNO, IOS, spirometry, and C-ACT results were correlated with childhood asthma with and without control. Results: Uncontrolled asthmatic children had abnormal FeNO, IOS, and spirometric values compared with control subjects ( Conclusion: A combined use of FeNO and IOS measurements strongly predicts childhood asthma with or without control.

Indexed as

allergic asthmaasthma controlfractional exhaled nitric oxideimpulse oscillometrypulmonary function

Identifiers

PMID35783300
PMCPMC9247317
OpenAlexW4283066659

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.