Evidence map›Paper›PMID 35783249›Full record

ArticleWorld neurosurgery: X2022

Comparing Fusion Rates Between Fresh-Frozen and Freeze-Dried Allografts in Anterior Cervical Discectomy and Fusion.

Derron Yu, Paramjyot Singh Panesar, Connor Delman, Benjamin W Van, Machelle D Wilson, Hai Van Le, Rolando Roberto, Yashar Javidan, Eric O Klineberg

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World neurosurgery: X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Derron YuSpine Center, University of California, Davis, Sacramento, California, USA.
Paramjyot Singh PanesarSpine Center, University of California, Davis, Sacramento, California, USA.
Connor DelmanSpine Center, University of California, Davis, Sacramento, California, USA.
Benjamin W VanSpine Center, University of California, Davis, Sacramento, California, USA.
Machelle D WilsonSpine Center, University of California, Davis, Sacramento, California, USA.
Hai Van LeSpine Center, University of California, Davis, Sacramento, California, USA.
Rolando RobertoSpine Center, University of California, Davis, Sacramento, California, USA.
Yashar JavidanSpine Center, University of California, Davis, Sacramento, California, USA.
Eric O KlinebergSpine Center, University of California, Davis, Sacramento, California, USA.
University of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this retrospective study is to compare the fusion rates in anterior cervical discectomy and fusion surgery using freeze-dried versus fresh-frozen allografts. Methods: The study comprised 79 patients. Fifty-one patients received freeze-dried allograft (106 total spinal levels) and 28 patients received fresh-frozen allograft (50 total spinal levels). Fusion was assessed through trabecular bridging on follow-up anterior-posterior/lateral radiographs. Trabecular bridging was assessed on the superior and inferior borders of each spinal level and given a fusion grade. Complete fusion is defined as >50% bridging between superior and inferior borders of the bone graft; union is complete fusion in <26 weeks; delayed union is complete fusion after 26 weeks; and fibrous union is <50% bridging at ≥1 borders over 52 weeks. Results: All spinal levels reached complete fusion for both graft types. Of the freeze-dried treated cervical spinal levels, 77.35% (82/106) reached union (adequate trabecular bridging within 6 months) without delay compared with 80% (35/50) for the fresh-frozen bone graft group ( Conclusions: From this study, freeze-dried and fresh-frozen allografts showed comparable rates of union, and both allografts can be used interchangeably for anterior cervical discectomy and fusion.

Indexed as

ACDFACDF, Anterior cervical discectomy and fusionAllograftsAP/Lat, Anterior-posterior/lateralBMP, Bone morphogenic proteinCervical radiculopathyCT, Computed tomographyFreeze-dried allograftsFresh-frozenFusion ratesNDI, Neck Disability IndexNSAID, Nonsteroidal antiinflammatory drugSpine

Identifiers

PMID35783249
PMCPMC9243252
OpenAlexW4281745666

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.