Evidence map›Paper›PMID 35783189›Full record

ArticleOxidative medicine and cellular longevity2022

HSPA12A Stimulates p38/ERK-AP-1 Signaling to Promote Angiogenesis and Is Required for Functional Recovery Postmyocardial Infarction.

Tingting Li, Jun Wu, Wansu Yu, Qian Mao, Hao Cheng, Xiaojin Zhang, Yuehua Li, Chuanfu Li, Zhengnian Ding, Li Liu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Tingting LiDepartment of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jun WuDepartment of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wansu YuDepartment of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qian MaoDepartment of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hao ChengDepartment of Anesthesiology, The First Affiliated Hospital with Wannan Medical College, Wuhu, China.
Xiaojin ZhangDepartment of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yuehua LiKey Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing, China.
Chuanfu LiDepartment of Surgery, East Tennessee State University, Johnson City, TN, USA.
Zhengnian DingDepartment of Anesthesiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0003-4108-6034
Li LiuDepartment of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0002-8054-562X
Jiangsu Province Hospital · CNEast Tennessee State University · USNanjing Medical University · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis plays a critical role in wound healing postmyocardial infarction (MI). However, there is still a lack of ideal angiogenic therapeutics for rescuing ischemic hearts clinically, suggesting that a more understanding regarding angiogenesis regulation is urgently needed. Heat shock protein A12A (HSPA12A) is an atypical member of the HSP70 family. Here, we demonstrated that HSPA12A was upregulated during endothelial tube formation, a characteristic of

Indexed as

Myocardial InfarctionTranscription Factor AP-1AnimalsEndothelial CellsExtracellular Signal-Regulated MAP KinasesHeat-Shock ProteinsHSP70 Heat-Shock ProteinsMiceNeovascularization, Pathologicp38 Mitogen-Activated Protein KinasesVascular Endothelial Growth Factor AExtracellular Signal-Regulated MAP KinasesHeat-Shock ProteinsHSP70 Heat-Shock ProteinsHspa12a protein, mousep38 Mitogen-Activated Protein KinasesTranscription Factor AP-1Vascular Endothelial Growth Factor A

Identifiers

PMID35783189
PMCPMC9247843
OpenAlexW4283399627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.