Evidence map›Paper›PMID 35783088›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2021

Hyperspectral Microscopic Imaging for the Detection of Head and Neck Squamous Cell Carcinoma on Histologic Slides.

Ling Ma, Ximing Zhou, James V Little, Amy Y Chen, Larry L Myers, Baran D Sumer, Baowei Fei

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. A Video Transformer Network for Thyroid Cancer Detection on Hyperspectral Histologic Images.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  10. Article
  11. Article
  12. Unsupervised Super Resolution Network for Hyperspectral Histologic Imaging.Proceedings of SPIE--the International Society for Optical Engineering
    Article
  13. Thyroid Carcinoma Detection on Whole Histologic Slides Using Hyperspectral Imaging and Deep Learning.Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Ling MaCenter for Imaging and Surgical Innovation and Department of Bioengineering, University of Texas at Dallas.
Ximing ZhouCenter for Imaging and Surgical Innovation and Department of Bioengineering, University of Texas at Dallas.
James V LittleDepartment of Pathology and Laboratory Medicine, Emory University.
Amy Y ChenDepartment of Otolaryngology, Emory University.
Larry L MyersDepartment of Otolaryngology, University of Texas Southwestern Medical Center.
Baran D SumerDepartment of Otolaryngology, University of Texas Southwestern Medical Center.
Baowei FeiCenter for Imaging and Surgical Innovation and Department of Bioengineering, University of Texas at Dallas.
Emory University · USThe University of Texas Southwestern Medical Center · USSouthwestern Medical Center · USThe University of Texas at Dallas · USTianjin University · CN

Funding

Image-guided Intravascular Robotic System for Mitral Valve Repair and ImplantsR01HL140325 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI DESAI, JAYDEV P., FEI, BAOWEI · 2018 to 2021
$3.0M
ACADEMIC-INDUSTRIAL PARTNERSHIP FOR TRANSLATION OF PET/TRUS GUIDED INTERVENTIONR01CA204254 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2017 to 2021
$2.0M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
STAN-CT: Standardization and Normalization of CT images for Lung Cancer PatientsR21CA231911 · NCI · UNIVERSITY OF KENTUCKY · PI CHEN, JIN, FEI, BAOWEI · 2019 to 2020
$389k
NCI NIH HHS R01 CA156775NCI NIH HHS R01 CA204254NCI NIH HHS R21 CA231911NHLBI NIH HHS R01 HL140325
6 · The paper itself

Abstract

The purpose of this study is to investigate hyperspectral microscopic imaging and deep learning methods for automatic detection of head and neck squamous cell carcinoma (SCC) on histologic slides. Hyperspectral imaging (HSI) cubes were acquired from pathologic slides of 18 patients with SCC of the larynx, hypopharynx, and buccal mucosa. An Inception-based two-dimensional convolutional neural network (CNN) was trained and validated for the HSI data. The automatic deep learning method was tested with independent data of human patients. This study demonstrated the feasibility of using hyperspectral microscopic imaging and deep learning classification to aid pathologists in detecting SCC on histologic slides.

Indexed as

classificationconvolutional neural networkdeep learningdigital pathologyhead and neck cancerhistologyHyperspectral microscopic imaging

Identifiers

PMID35783088
PMCPMC9248908
OpenAlexW3130214264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.