Evidence map›Paper›PMID 35782893›Full record

ArticleHepatology forum2021

Hepatitis E virus IgG seroprevalence in liver transplant patients: A retrospective single-center experience.

Ferit Celik, Ali Senkaya, Nalan Gulsen Unal, Seymur Aslanov, Alper Uysal, Aysin Zeytinoglu, Ilker Turan, Murat Zeytunlu, Omer Ozutemiz, Ulus Salih Akarca and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Hepatology forum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ferit CelikDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0003-4459-7657
Ali SenkayaDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0002-5787-3422
Nalan Gulsen UnalDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0001-8870-2450
Seymur AslanovDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0001-7520-6650
Alper UysalDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0002-5473-9383
Aysin ZeytinogluDepartment of Medical Microbiology, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0003-4174-9539
Ilker TuranDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0001-8998-1965
Murat ZeytunluDepartment of General Surgery, Ege University School of Medicine, Izmir, Turkey.ORCID https://orcid.org/0000-0001-6911-8953
Omer OzutemizDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0002-6960-4043
Ulus Salih AkarcaDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0002-7020-5816
Zeki KarasuDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0002-4974-7944
Fulya GunsarDivision of Gastroenterology, Department of Internal Medicine, Ege University Izmir, Turkey.ORCID https://orcid.org/0000-0002-6002-4819
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Hepatitis E virus (HEV) may cause chronic liver disease in solid organ transplant recipients. We determined HEV seroprevalence and associated factors in liver transplant recipients. Materials and Methods: Patients followed at the outpatient clinic of liver transplantation between January 2019 and January 2020 were screened retrospectively for HEV serology (HEV immunoglobulin M [IgM] and HEV immunoglobulin G [IgG]). Results: Of the 150 patients (male/female, 104/46; age, 55.4±13.2 years), anti-HEV IgG was positive in 31 (20.7%), and anti-HEV IgM was negative in all. The mean time after liver transplantation (72 [48%] deceased and 78 [52%] living donors) was 81±78.5 months. Drinking water consisted of carboy and tap water in 88 (58.7%) and 62 patients (41.3%), respectively. Of the patients, 120 (80%) and 30 (20%) lived in urban and rural areas, respectively. On comparison, the difference between positive and negative anti-HEV IgG groups in terms of age, place of birth, water supply, and donor type was statistically significant (p=0.007, p=0.000, p=0.034, and p=0.049, respectively). Conclusion: HEV seroprevalence was more frequent in liver transplant recipients compared with the normal population. Older age, water supply, and place of birth were risk factors for HEV seroprevalence.

Indexed as

Anti-HEV IgGliver transplantationseroprevalence

Identifiers

PMID35782893
PMCPMC9138931
OpenAlexW3121127095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.