Evidence map›Paper›PMID 35782696›Full record

ArticleHong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao2022

Heart rate variability, exercise capacity and levels of daily physical activity in children and adolescents with mild-to-moderate cystic fibrosis.

Pitiguara de Freitas Coelho, Roberta Ribeiro Batista Barbosa, Rodrigo Dos Santos Lugao, Fernanda Mayrink Gonçalves Liberato, Pâmela Reis Vidal, Roberta de Cássia Nunes Cruz Melotti, Márcio Vinícius Fagundes Donadio

Open access · diamondAbstract read
In one paragraph

Article in Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. The 2025 European Cystic Fibrosis Society position statement on physical activity assessment in cystic fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Pitiguara de Freitas CoelhoEscola Superior de Ciˆencias da Santa Casa de Misericórdia de Vitória - EMESCAM, Vitória, Espírito Santo, Brazil.
Roberta Ribeiro Batista BarbosaEscola Superior de Ciˆencias da Santa Casa de Misericórdia de Vitória - EMESCAM, Vitória, Espírito Santo, Brazil.
Rodrigo Dos Santos LugaoEscola Superior de Ciˆencias da Santa Casa de Misericórdia de Vitória - EMESCAM, Vitória, Espírito Santo, Brazil.
Fernanda Mayrink Gonçalves LiberatoCystic Fibrosis Reference Center, Hospital Infantil Nossa Senhora da Glória, Vitória, Espírito Santo, Brazil.
Pâmela Reis VidalEscola Superior de Ciˆencias da Santa Casa de Misericórdia de Vitória - EMESCAM, Vitória, Espírito Santo, Brazil.
Roberta de Cássia Nunes Cruz MelottiCystic Fibrosis Reference Center, Hospital Infantil Nossa Senhora da Glória, Vitória, Espírito Santo, Brazil.
Márcio Vinícius Fagundes DonadioLaboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica, do Rio Grande do Sul (PUCRS), Porto Alegre, Rio Grande do Sul, Brazil.
Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória · BRHospital Nossa Senhora da Conceição · BRPontifícia Universidade Católica do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autonomic nervous system balance is altered in cystic fibrosis (CF), although its influence on physical fitness has been poorly explored. Objective: This study aimed to evaluate the association of heart rate variability (HRV) with exercise capacity and levels of daily physical activity in children and adolescents with mild-to-moderate CF. Methods: A cross-sectional study including individuals with CF aged 6-18 years, not under CFTR modulator therapy, was performed. Sociodemographic (age, sex) and clinical information (airway colonization, pancreatic insufficiency, and genotyping) were collected. In addition, exercise capacity (modified shuttle test - MST), lung function (spirometry), body composition (bioimpedance), levels of daily physical activity (5-day accelerometer), and HRV (both at rest and during the MST) were evaluated. Results: 30 individuals (20 females) aged Conclusion: HRV correlates with lung function, exercise capacity and levels of daily physical activity in children and adolescents with CF. The study highlights the influence of CF on autonomic function and suggests HRV measurement as an easy tool to be used in clinical settings as an alternative marker to monitor CF individuals.

Indexed as

Cystic fibrosisexercise capacityheart rate variabilitymodified shuttle testpediatrics

Identifiers

PMID35782696
PMCPMC9244599
OpenAlexW3166429334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.