Evidence map›Paper›PMID 35782680›Full record

ReviewSports medicine and health science2021

Frailty: Past, present, and future?

Dongmin Kwak, LaDora V Thompson

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sports medicine and health science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06064227 (The Effect of Health Promotion Comprehensive Education Intervention on the Frailty Levels of Elderly Family Caregivers), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06064227 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Health Promotion Comprehensive Education Intervention on the Frailty Levels of Elderly Family Caregivers

TypeinterventionalSponsorFatma Banu DemirdasRan2023 to 2023Enrolled88ConditionsFrailty, Caregiver Burden, Frail Elderly SyndromeArmstraining intervention
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Risk aversion and time preference among elderly: does frailty matter?International journal of health economics and management · 2026
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  5. Development and validation of an electronic health record-based frailty index in the UK Biobank.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dongmin KwakDivision of Sport Science, Hanyang University, Ansan, South Korea.
LaDora V ThompsonDepartment of Physical Therapy and Athletic Training, Boston University, Boston, MA, USA.

Funding

Frailty: Prediction of Onset and ProgressionR56AG067724 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI BROWN-BORG, HOLLY M., THOMPSON, LADORA V · 2020 to 2020
$759k
NIA NIH HHS R56 AG067724
6 · The paper itself

Abstract

The prevalence of frailty across the world in older adults is increasing dramatically and having frailty places a person at increased risk for many adverse health outcomes, including impaired mobility, falls, hospitalizations, and mortality. Globally, the concept of frailty is gaining attention and the scientific field has made great strides in identifying and conceptually defining frailty through consensus conferences, in advancing the overall science of frailty by drawing on basic science discoveries including concepts surrounding the hallmarks of aging, resilience, and intrinsic capacities, and in identifying the many challenges faced by professionals within diverse clinical settings. Currently, it is thought that frailty is preventable, thus the identification of a person's degree of frailty is vital. Identification of frailty is achievable through widely used frailty screening tools, which are valid, reliable, and easy to use. Following the identification of a person's degree of frailty, targeted intervention strategies, such as physical activity programs must be implemented. In this perspective, we provide a historical perspective of the frailty field since the last quarter of the 20th century to present. We identify the proposed underlying pathophysiology of multiple physiological systems, including compromised homeostasis and resilience. Next, we outline the available screening tools for frailty with a physical performance assessment and highlight specific benefits of physical activity. Lastly, we discuss current scientific evidence supporting the physical activity recommendations for the aging population and for older adults with frailty. The goal is to emphasize early detection of frailty and stress the value of physical activity.

Indexed as

2018 PAGAC Scientific ReportFrailty phenotypeIntrinsic capacityMulticomponent physical activity programsPhysical activity guidelines

Identifiers

PMID35782680
PMCPMC9219322

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.