ArticleClinical pathology (Thousand Oaks, Ventura County, Calif.)
Morphological and Ancillary Features of Uterine Leiomyosarcoma: Case Report.
Article in Clinical pathology (Thousand Oaks, Ventura County, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Ultrastructural and Immunohistochemical Study of a Gastric Bizarre Leiomyoma: Bizarre Nuclei and Prominent Cytoplasmic Processes Extending Into and Displacing the Stroma.Pathology international · 2025Article
- Surgical treatment of primary intracranial and extracranial communicating leiomyosarcoma: a case report.Frontiers in oncology · 2025Article
- A bibliometric analysis of literatures on uterine leiomyosarcoma in the last 20 years.Frontiers in oncology · 2024Article
- Flares of Confusion: A Case Report of Uterine Leiomyoma and Angiomatosis Complexity on Imaging.Cureus · 2023Article
- Deep Venous Thrombosis as the Sentinel Event Unmasking a Uterine Leiomyosarcoma in a Postmenopausal Woman: A Case Report and Review of the Literature.Case reports in oncologyArticle
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
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Abstract
We report a rare case of giant uterine leiomyosarcoma in a postmenopausal woman, whose diagnosis was initially suspected at the evaluation of the abdominal efusion, and confirmed after the pathological examination of the uterus in association with the ancillary tests. The evaluation of the abdominal fluid showed single or clusters of malignant, round or spindle-shaped cells. On microscopic examination of the surgical specimen, a dense cell proliferation of spindle cells, with moderate to severe nuclear pleomorphism and significant mitotic activity was observed. Immunohistochemical evaluation demonstrated the loss of myocytic differentiation by focal, weakly positive expression of smooth muscle actin and desmin. The data presented in this case emphasize the relevance of the cytological examination, although the latter has only indicative value, especially since it is an aggressive tumor, frequently associated with mutant expression of p53. In our case, the first indication of the presence of uterine sarcoma was given by the presence of atypical cells in the peritoneal fluid.
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Registered trials
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