Evidence map›Paper›PMID 35782581›Full record

ArticleLeukemia research reports2022

AML with BCR-ABL1 Fusion treated with Imatinib, a Hypomethylating Agent and Venetoclax.

Soon Khai Low, Suparna Nanua, Mehul Patel, Anne S Renteria

Open access · goldAbstract readCase Reports
In one paragraph

Article in Leukemia research reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Soon Khai LowDepartment of Internal Medicine, Rochester General Hospital, NY, United States.
Suparna NanuaDepartment of Pathology, Rochester General Hospital, NY, United States.
Mehul PatelHematology Oncology, Lipson Cancer Institute, Rochester General Hospital, NY, United States.
Anne S RenteriaAcute Leukemia & Stem Cell Transplant and Cellular Therapy Programs, Lipson Cancer Institute, Rochester General Hospital, NY, United States.
Rochester General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A patient with history of myelodysplastic syndrome (MDS) presented with multifocal pneumonia and was found to have Philadelphia chromosomepositive (Ph+) acute myeloid leukemia (AML). A tyrosine kinase inhibitor (TKI) was added to decitabine and venetoclax combination, providing a molecular and cytogenetic complete response despite additional cytogenetic and molecular abnormalities. She remains in remission after eleven cycles of treatment. Our report describes the tolerability and success of a triplet regimen that incorporates a TKI to a backbone of decitabine and venetoclax in a patient with high-risk disease and with significant comorbidities.

Indexed as

Acute myeloid leukemiaDecitabinePhiladelphia chromosoomeTyrosine kinase inhibitorVenetoclax

Identifiers

PMID35782581
PMCPMC9240361
OpenAlexW4283310920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.