Evidence map›Paper›PMID 35782557›Full record

ReviewFrontiers in veterinary science2022

Neurostimulation as a Method of Treatment and a Preventive Measure in Canine Drug-Resistant Epilepsy: Current State and Future Prospects.

Marta Nowakowska, Muammer Üçal, Marios Charalambous, Sofie F M Bhatti, Timothy Denison, Sebastian Meller, Gregory A Worrell, Heidrun Potschka, Holger A Volk

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Epilepsy in Asian countries.Acta epileptologica · 2023
    Review
  6. Article
  7. Status Epilepticus After Electrocution Injury in a Dog.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Marta NowakowskaResearch Unit of Experimental Neurotraumatology, Department of Neurosurgery, Medical University of Graz, Graz, Austria.
Muammer ÜçalResearch Unit of Experimental Neurotraumatology, Department of Neurosurgery, Medical University of Graz, Graz, Austria.
Marios CharalambousDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hanover, Germany.
Sofie F M BhattiSmall Animal Department, Faculty of Veterinary Medicine, Small Animal Teaching Hospital, Ghent University, Merelbeke, Belgium.
Timothy DenisonDepartment of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom.
Sebastian MellerDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hanover, Germany.
Gregory A WorrellDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
Heidrun PotschkaFaculty of Veterinary Medicine, Institute of Pharmacology, Toxicology and Pharmacy, Ludwig-Maximilians-University, Munich, Germany.
Holger A VolkDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hanover, Germany.
University of Veterinary Medicine Hannover, Foundation · DEMedical University of Graz · ATGhent University · BELudwig-Maximilians-Universität München · DEMayo Clinic in Arizona · USUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modulation of neuronal activity for seizure control using various methods of neurostimulation is a rapidly developing field in epileptology, especially in treatment of refractory epilepsy. Promising results in human clinical practice, such as diminished seizure burden, reduced incidence of sudden unexplained death in epilepsy, and improved quality of life has brought neurostimulation into the focus of veterinary medicine as a therapeutic option. This article provides a comprehensive review of available neurostimulation methods for seizure management in drug-resistant epilepsy in canine patients. Recent progress in non-invasive modalities, such as repetitive transcranial magnetic stimulation and transcutaneous vagus nerve stimulation is highlighted. We further discuss potential future advances and their plausible application as means for preventing epileptogenesis in dogs.

Indexed as

deep brain stimulationdogsdrug-resistant epilepsyepileptogenesisseizuretranscranial magnetic stimulationvagus nerve stimulation

Identifiers

PMID35782557
PMCPMC9244381
OpenAlexW4283015614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.