Evidence map›Paper›PMID 35782381›Full record

ArticleFrontiers in molecular neuroscience2022

The Voltage-Gated Calcium Channel EGL-19 Acts on Glia to Drive Olfactory Adaptation.

Du Chen, Hankui Cheng, Siyan Liu, Umar Al-Sheikh, Yuedan Fan, Duo Duan, Wenjuan Zou, Linhui Zhu, Lijun Kang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Dendrite glia interactions: lessons from theFrontiers in cell and developmental biology · 2025
    Review
  3. Glia Development and Function in the NematodeCold Spring Harbor perspectives in biology · 2024
    Review
  4. Glial KCNQ KNeuron · 2024
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Du ChenDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Hankui ChengDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Siyan LiuDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Umar Al-SheikhDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Yuedan FanDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Duo DuanDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Wenjuan ZouDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Linhui ZhuDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Lijun KangDepartment of Neurobiology and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CNZhejiang Lab · CNZhejiang University · CN

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Calcium channelopathies have been strongly linked to cardiovascular, muscular, neurological and psychiatric disorders. The voltage-gated calcium channels (VGCC) are vital transducers of membrane potential changes to facilitate the dynamics of calcium ions and release of neurotransmitter. Whether these channels function in the glial cell to mediate calcium variations and regulate behavioral outputs, is poorly understood. Our results showed that odorant and mechanical stimuli evoked robust calcium increases in the amphid sheath (AMsh) glia from

Indexed as

adaptationcalcium channelgliaglia-neuron interactionolfaction

Identifiers

PMID35782381
PMCPMC9247319
OpenAlexW4283074436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.