Evidence map›Paper›PMID 35782375›Full record

ReviewHepatology forum2022

Prevention of hepatocellular carcinoma and monitoring of high-risk patients.

Eda Kaya, Guillermo Daniel Mazzolini, Yusuf Yilmaz, Ali Canbay

Open access · greenAbstract readReview
In one paragraph

Review in Hepatology forum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. [Study on the value of abnormal prothrombin in the diagnosis of HBV-related hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eda KayaSection of Gastroenterology and Hepatology, University, Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, Bochum, Germany.ORCID https://orcid.org/0000-0002-9293-2811
Guillermo Daniel MazzoliniLaboratory of Gene Therapy, Instituto de Investigaciones en Medicina Traslacional, CONICET-Universidad Austral, Buenos Aires, Argentina; Liver Unit, Hospital Universitario Austral, Universidad Austral, Argentina.ORCID https://orcid.org/0000-0002-1450-8441
Yusuf YilmazDepartment of Gastroenterology, School of Medicine, Marmara University, Istanbul, Turkey.ORCID https://orcid.org/0000-0003-4518-5283
Ali CanbaySection of Gastroenterology and Hepatology, University, Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, Bochum, Germany.ORCID https://orcid.org/0000-0001-6069-7899
Universitätsklinikum Knappschaftskrankenhaus Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) accounts for some 80% of primary liver tumors. According to recent data, HCC is the sixth most common type of cancer and the third leading cause of cancer-related mortality worldwide. Risk factors for HCC include the presence of the hepatitis B virus, hepatitis C virus, non-alcoholic fatty liver disease, and exposure to noxious agents, such as alcohol, or toxins, such as aflatoxin, which are considered preventable etiologies of HCC. Monitoring strategies are needed for patients at risk of developing HCC. There is a consensus on routine monitoring of cirrhotic patients due to definitive evidence of a significantly high rate of progression to HCC; however, the appropriate surveillance of patients with advanced fibrosis remains a topic of discussion. Nevertheless, adherence to a strict observation protocol is the cornerstone of early detection and treatment with curative options for patients with a high risk of developing HCC. This review examines prevention strategies, risk factors, and surveillance based on current guidelines.

Indexed as

Hepatitis Bhepatitis Chepatocellular carcinomanon-alcoholic fatty liver diseasepreventionsurveillance

Identifiers

PMID35782375
PMCPMC9138915
OpenAlexW3210903831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.