ReviewAsian journal of pharmaceutical sciences2022
Application of chitosan-based nanoparticles in skin wound healing.
Review in Asian journal of pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed.
- Future perspectives of propolis-chitosan biomembranes in wound healing: molecular mechanism, formulation and therapeutic properties.RSC advances · 2026Review
- Camel Milk Extracellular Vesicles as Engineered Biogenic Particles: Thermosensitive Hydrogel Integration for Optimized Wound Delivery and Tissue Regeneration.Pharmaceutics · 2026Article
- Promising Natural Polymer-Based Dressings for Diabetic Foot Ulcers: Mechanisms, Preclinical Studies, and Clinical Applications.Pharmaceutics · 2026Review
- Green Synthesis of Iron Oxide-Chitosan-Glutathione Nanosystem for Wound Healing Enhancement.Cell biochemistry and biophysics · 2026Article
- Medical dressing inspired by dandelion "smashed for external application" therapy for diabetic wound care.Materials today. Bio · 2026Article
- Biosynthesis of copper, cobalt, and zinc oxide nanoparticles using the seed extract ofRSC advances · 2026Article
- Time-dependent effects of topical mucopolysaccharide polysulfate and silver sulfadiazine on wound healing in a rat excisional wound model.Joint diseases and related surgery · 2026Article
- A Simple Ionic-Gelation Method for Chitosan Nanoparticle Synthesis and Standardized Protocols for Biological Safety Assessment: Antibacterial Activity, Phytotoxicity, and Biocompatibility.International journal of molecular sciences · 2026Article
- MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.Materials today. Bio · 2026Article
- Path Analysis Results on Bone Markers That Influence Accelerated Bone Remodeling: An Experimental Study.Clinical and experimental dental research · 2026Article
- Bacterial Nanocellulose Wound Dressings with Gentamicin-Loaded Chitosan Nanoparticles for Surgical Site Infection Management.Polymers · 2026Article
- Nanostructured Lipid Carrier-Gels for Wound Healing: A Narrative Review of Formulation Strategies, Mechanisms, and Translational Potential.Nanotechnology, science and applications · 2026Review
- Review of recent advances in chitosan- and hyaluronic-acid-based wound dressings: fabrication, application, and types.Frontiers in pharmacology · 2026Review
- Review
- Application of chitosan-based nanogels for dermal and transdermal delivery systems.Journal of materials science. Materials in medicine · 2025Review
- Topical and transdermal lipid-polymer hybrid nanoparticles (LPN): an integration in advancing dermatological treatments.Drug delivery and translational research · 2025Review
- Chitosan Nanoformulations of Mycosporine-like Amino Acid (MAA)-Rich Extracts fromInternational journal of molecular sciences · 2025Article
- Review
- The cutting-edge progress of novel biomedicines in ovulatory dysfunction therapy.Acta pharmaceutica Sinica. B · 2025Review
- Tissue Regeneration of Radiation-Induced Skin Damages Using Protein/Polysaccharide-Based Bioengineered Scaffolds and Adipose-Derived Stem Cells: A Review.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rising prevalence of impaired wound healing and the consequential healthcare burdens have gained increased attention over recent years. This has prompted research into the development of novel wound dressings with augmented wound healing functions. Nanoparticle (NP)-based delivery systems have become attractive candidates in constructing such wound dressings due to their various favourable attributes. The non-toxicity, biocompatibility and bioactivity of chitosan (CS)-based NPs make them ideal candidates for wound applications. This review focusses on the application of CS-based NP systems for use in wound treatment. An overview of the wound healing process was presented, followed by discussion on the properties and suitability of CS and its NPs in wound healing. The wound healing mechanisms exerted by CS-based NPs were then critically analysed and discussed in sections, namely haemostasis, infection prevention, inflammatory response, oxidative stress, angiogenesis, collagen deposition, and wound closure time. The results of the studies were thoroughly reviewed, and contradicting findings were identified and discussed. Based on the literature, the gap in research and future prospects in this research area were identified and highlighted. Current evidence shows that CS-based NPs possess superior wound healing effects either used on their own, or as drug delivery vehicles to encapsulate wound healing agents. It is concluded that great opportunities and potentials exist surrounding the use of CSNPs in wound healing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.