Evidence map›Paper›PMID 35782312›Full record

ArticleJournal of molecular structure2022

Crystallographic study, biological assessment and POM/Docking studies of pyrazoles-sulfonamide hybrids (PSH): Identification of a combined Antibacterial/Antiviral pharmacophore sites leading to

Mohammed Chalkha, Asmae Nakkabi, Taibi Ben Hadda, Malika Berredjem, Abdelfattah El Moussaoui, Mohamed Bakhouch, Mohamed Saadi, Lahcen El Ammari, Faisal A Almalki, Hamid Laaroussi and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular structure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 5 countries.

Mohammed ChalkhaEngineering Laboratory of Organometallic and Molecular Materials and Environment (LIMOME), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, P.O. Box 1796, Atlas, Fez, 30000, Morocco.
Asmae NakkabiEngineering Laboratory of Organometallic and Molecular Materials and Environment (LIMOME), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, P.O. Box 1796, Atlas, Fez, 30000, Morocco.
Taibi Ben HaddaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Malika BerredjemLaboratoire de chimie organique appliquée (LCOA), Groupe de Synthèse de biomolécules et modélisation moléculaire, Université Badji-Mokhtar Annaba, BP 12, Annaba 23000, Algérie.
Abdelfattah El MoussaouiLaboratory of Biotechnology, Environment, Agri-Food, and Health (LBEAS), Faculty of Sciences, University Sidi Mohamed Ben Abdellah (USMBA), Fez 30050, Morocco.
Mohamed BakhouchLaboratory of Bioorganic Chemistry, Department of Chemistry, Faculty of Sciences, Chouaïb Doukkali University, El Jadida 24000, Morocco.
Mohamed SaadiLaboratoire de Chimie Appliquée des Matériaux, Centres des Sciences des Matériaux, Faculty of Science, Mohammed V University, Avenue Ibn Battouta, BP. 1014, 100090 Rabat, Morocco.
Lahcen El AmmariLaboratoire de Chimie Appliquée des Matériaux, Centres des Sciences des Matériaux, Faculty of Science, Mohammed V University, Avenue Ibn Battouta, BP. 1014, 100090 Rabat, Morocco.
Faisal A AlmalkiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Hamid LaaroussiLaboratory of Applied Chemistry & Environment, Faculty of Sciences, Mohammed Premier University, MB 524, Oujda 60000, Morocco.
Violeta JevtovicDepartment of Chemistry, College of Science, University of Hail, Hail 81451, Saudi Arabia.
Mohamed El YazidiEngineering Laboratory of Organometallic and Molecular Materials and Environment (LIMOME), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, P.O. Box 1796, Atlas, Fez, 30000, Morocco.
Sidi Mohamed Ben Abdellah University · MAMohammed V University · MAUmm al-Qura University · SABadji Mokhtar-Annaba University · DZChouaib Doukkali University · MAMohamed I University · MAUniversité Moulay Ismail de Meknes · MAUniversity of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery and development of new potent antimicrobial and antioxidant agents is an essential lever to protect living beings against pathogenic microorganisms and free radicals. In this regard, new functionalized pyrazoles have been synthesized using a simple and accessible approach. The synthesized aminobenzoylpyrazoles

Indexed as

Antimicrobial/Antioxidant bioactivityDocking studyIdentification of the pharmacophore sitesPetra/Osiris/Molinspiration (POM) analysesPOM, Petra/Osiris/MolinspirationPSH, Pyrazoles-Sulfonamide HybridsPyrazole Linked Sulfonamide Conjugates

Identifiers

PMID35782312
PMCPMC9237569
OpenAlexW4283662586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.