Evidence map›Paper›PMID 35782149›Full record

ArticleFrontiers in cellular and infection microbiology2022

An Unusual U2AF2 Inhibits Splicing and Attenuates the Virulence of the Human Protozoan Parasite

Gretter González-Blanco, Guillermina García-Rivera, Patricia Talmás-Rohana, Ester Orozco, José Manuel Galindo-Rosales, Cristina Vélez, Odila Salucedo-Cárdenas, Elisa Azuara-Liceaga, Mario Alberto Rodríguez-Rodríguez, Tomoyoshi Nozaki and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Microbiology (Reading, England) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Gretter González-BlancoDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Guillermina García-RiveraDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Patricia Talmás-RohanaDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Ester OrozcoDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
José Manuel Galindo-RosalesDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Cristina VélezDepartamento de Biología Celular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Odila Salucedo-CárdenasDepartamento de Histología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Mexico.
Elisa Azuara-LiceagaPosgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, CDMX, Mexico.
Mario Alberto Rodríguez-RodríguezDepartamento de Biología Celular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Tomoyoshi NozakiLaboratory of Biomedical Chemistry, Department of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Jesús ValdésDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), CDMX, Mexico.
Center for Research and Advanced Studies of the National Polytechnic Institute · MXThe University of Tokyo · JPUniversidad Autónoma de la Ciudad de México · MXUniversidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Entamoeba histolyticaAnimalsDysentery, AmebicHumansMetronidazoleProtozoan ProteinsRNA SplicingRNA Splicing FactorsSplicing Factor U2AFMetronidazoleProtozoan ProteinsRNA Splicing FactorsSplicing Factor U2AFintron retentionKH-QUA2 motifsprotein–protein interactionsprotein–RNA bindingsplicing complex E to A transition

Identifiers

PMID35782149
PMCPMC9247205
OpenAlexW4283031695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.