Evidence map›Paper›PMID 35782027›Full record

ReviewReumatologia2022

Adhesion molecules: a way to understand lupus.

Karolina Nowak, Olga Gumkowska-Sroka, Przemysław Kotyla

Abstract readReview
In one paragraph

Review in Reumatologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karolina NowakDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.ORCID https://orcid.org/0000-0003-1011-3992
Olga Gumkowska-SrokaSt Barbara Regional Specialist Hospital No. 5 in Sosnowiec, Poland.ORCID https://orcid.org/0000-0001-6211-3762
Przemysław KotylaDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.ORCID https://orcid.org/0000-0001-8376-6527

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus is a connective disease in which all vitally important organs may be affected. The etiology of the disease is largely unknown and almost all immunological mechanisms have been proposed as the pathophysiological background of the disease. Among them, endothelial damage and dysfunction seem to play a pivotal role. Endothelial damage can be accurately measured using adhesion molecules such asintercellular adhesion molecule (ICAM), vascular cell adhesion molecule (VCAM), platelet endothelial cell adhesion molecule (PECAM) and selectins. In this review we discuss the role of well-known cellular adhesion molecules as pathogenic factors in disease development as well as disease activity biomarkers.

Indexed as

cell adhesion moleculesendothelial biomarkersendothelial dysfunctionsystemic lupus erythematosus

Identifiers

PMID35782027
PMCPMC9238314

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.