Evidence map›Paper›PMID 35782019›Full record

ArticleInternational journal of nanomedicine2022

Airspace Dimension Assessment with Nanoparticles (AiDA) in Comparison to Established Pulmonary Function Tests.

Madeleine Petersson-Sjögren, Jonas Jakobsson, H Laura Aaltonen, Hanna Nicklasson, Jenny Rissler, Gunnar Engström, Per Wollmer, Jakob Löndahl

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madeleine Petersson-SjögrenDivision of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, Lund, Sweden.ORCID 0000-0002-0355-256X
Jonas JakobssonDivision of Nuclear Physics, Department of Physics, Lund University, Lund, Sweden.ORCID 0000-0002-4833-8866
H Laura AaltonenDepartment of Translational Medicine, Medical Imaging and Physiology, Lund University, Malmö, Sweden.ORCID 0000-0002-4520-3229
Hanna NicklassonDepartment of Translational Medicine, Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Malmö, Sweden.
Jenny RisslerDivision of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, Lund, Sweden.ORCID 0000-0001-8650-4741
Gunnar EngströmDepartment of Clinical Sciences, Lund University, Malmö, Sweden.ORCID 0000-0002-8618-9152
Per WollmerDepartment of Translational Medicine, Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Malmö, Sweden.ORCID 0000-0003-2448-9931
Jakob LöndahlDivision of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, Lund, Sweden.ORCID 0000-0001-9379-592X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Airspace Dimensions Assessment with nanoparticles (AiDA) is a new method for non-invasive measurement of pulmonary distal airspaces. The aim of this study was to compare AiDA measurements with other pulmonary function variables to better understand the potential of AiDA in a clinical context. Methods: AiDA measurements and pulmonary function tests were performed in 695 subjects as part of the Swedish CArdioPulmonary bioImage Study. The measurement protocol included spirometry, measurement of diffusing capacity of carbon monoxide, oscillometry and pulmonary computed tomography. AiDA indices were compared to all other pulmonary examination measurements using multivariate statistical analysis. Results: Our results show that AiDA measurements were significantly correlated with other pulmonary function examination indices, although covariance was low. We found that AiDA variables explained variance in the data that other lung function variables only influenced to a minor extent. Conclusion: We conclude that the AiDA method provides information about the lung that is inaccessible with more conventional lung function techniques.

Indexed as

LungNanoparticlesCarbon MonoxideHumansRespiratory Function TestsTomography, X-Ray ComputedCarbon Monoxideaerosol nanoparticlesairspace dimension assessment with nanoparticlesCOPD diagnosticsdistal airspacesrespiratory diagnostics with nanoparticles

Identifiers

PMID35782019
PMCPMC9241766

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.