Evidence map›Paper›PMID 35781950›Full record

ArticleBiomedical optics express2022

Automated classification of otitis media with OCT: augmenting pediatric image datasets with gold-standard animal model data.

Guillermo L Monroy, Jungeun Won, Jindou Shi, Malcolm C Hill, Ryan G Porter, Michael A Novak, Wenzhou Hong, Pawjai Khampang, Joseph E Kerschner, Darold R Spillman and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Label-Free Optical Technologies for Middle-Ear Diseases.Bioengineering (Basel, Switzerland) · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Guillermo L MonroyBeckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801, USA.ORCID https://orcid.org/0000-0002-3669-8514
Jungeun WonBeckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801, USA.
Jindou ShiBeckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801, USA.
Malcolm C HillCarle Foundation Hospital, 611 W Park St., Urbana, IL 61801, USA.
Ryan G PorterCarle Foundation Hospital, 611 W Park St., Urbana, IL 61801, USA.
Michael A NovakCarle Foundation Hospital, 611 W Park St., Urbana, IL 61801, USA.
Wenzhou HongDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Pawjai KhampangDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Joseph E KerschnerDepartment of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Darold R SpillmanBeckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801, USA.ORCID https://orcid.org/0000-0001-9946-2659
Stephen A BoppartBeckman Institute for Advanced Science and Technology, 405 N Mathews Ave, Urbana, IL 61801, USA.ORCID https://orcid.org/0000-0002-9386-5630
Carle Foundation Hospital · USMedical College of Wisconsin · USUniversity of Illinois Urbana-Champaign · US

Funding

Partnership for Primary Care Imaging of the EarR01EB013723 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2011 to 2018
$6.4M
Otitis Media Diagnosis and TreatmentR01DC019412 · NIDCD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Stephen A Boppart, JOSEPH E KERSCHNER · 2022 to 2026
$2.6M
Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis MediaR01EB028615 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A, MAHADEVAN-JANSEN, ANITA · 2019 to 2022
$2.5M
NIBIB NIH HHS R01 EB013723NIBIB NIH HHS R01 EB028615NIDCD NIH HHS R01 DC019412
6 · The paper itself

Abstract

Otitis media (OM) is an extremely common disease that affects children worldwide. Optical coherence tomography (OCT) has emerged as a noninvasive diagnostic tool for OM, which can detect the presence and quantify the properties of middle ear fluid and biofilms. Here, the use of OCT data from the chinchilla, the gold-standard OM model for the human disease, is used to supplement a human image database to produce diagnostically relevant conclusions in a machine learning model. Statistical analysis shows the datatypes are compatible, with a blended-species model reaching ∼95% accuracy and F1 score, maintaining performance while additional human data is collected.

Identifiers

PMID35781950
PMCPMC9208614
OpenAlexW4280543865

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.