Evidence map›Paper›PMID 35781887›Full record

ArticleLasers in surgery and medicine2022

Segmentation of laser induced retinal lesions using deep learning (December 2021).

Eddie M Gil, Mark Keppler, Adam Boretsky, Vladislav V Yakovlev, Joel N Bixler

Open access · greenAbstract read
In one paragraph

Article in Lasers in surgery and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Eddie M GilDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas, USA.
Mark KepplerDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas, USA.
Adam BoretskySAIC, JBSA Fort Sam, Houston, Texas, USA.
Vladislav V YakovlevDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-4557-1013
Joel N BixlerAir Force Research Laboratory, JBSA Fort Sam, Houston, Texas, USA.
United States Army Institute of Surgical Research · USTexas A&M University · USUnited States Air Force Research Laboratory · US

Funding

Brillouin Microscope for Biomedical ResearchR01GM127696 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2018 to 2021
$1.1M
Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopyR21CA269099 · NCI · TEXAS ENGINEERING EXPERIMENT STATION · PI BEREZIN, MIKHAIL Y., YAKOVLEV, VLADISLAV V. · 2022 to 2024
$577k
Sensing local nano-environment with coherent Raman microspectroscopyR21GM142107 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2021 to 2022
$399k
NCI NIH HHS R21 CA269099NIGMS NIH HHS R01 GM127696NIGMS NIH HHS R21 GM142107
6 · The paper itself

Abstract

objectiveDetection of retinal laser lesions is necessary in both the evaluation of the extent of damage from high power laser sources, and in validating treatments involving the placement of laser lesions. However, such lesions are difficult to detect using Color Fundus cameras alone. Deep learning-based segmentation can remedy this, by highlighting potential lesions in the image.

methodsA unique database of images collected at the Air Force Research Laboratory over the past 30 years was used to train deep learning models for classifying images with lesions and for subsequent segmentation. We investigate whether transferring weights from models that learned classification would improve performance of the segmentation models. We use Pearson's correlation coefficient between the initial and final training phases to reveal how the networks are transferring features.

resultsThe segmentation models are able to effectively segment a broad range of lesions and imaging conditions.

conclusionDeep learning-based segmentation of lesions can effectively highlight laser lesions, making this a useful tool for aiding clinicians.

Indexed as

Deep LearningDatabases, FactualImage Processing, Computer-AssistedLasersdeep learningfundus imageslaser safetylaser tissue interactiontransfer learning

Identifiers

PMID35781887
PMCPMC9464686
OpenAlexW4283795701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.