ArticleMetabolomics : Official journal of the Metabolomic Society2022
Profiling of secondary metabolites and DNA typing of three different Annona cultivars grown in Egypt.
Article in Metabolomics : Official journal of the Metabolomic Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- A pharmaco-metabolomics study of Glycyrrhiza glabra, Boswellia sarca, and Acacia nilotica in acute allergic dermatitis.Inflammopharmacology · 2025Article
- Role of rich phenolics and betanin profiles from Opuntia ficus-indica fruits in the prevention of diabetic complications using metabolomics study.Scientific reports · 2025Article
- Appraisal terpenoids rich Boswellia carterri ethyl acetate extract in binary cyclodextrin oligomer nano complex for improving respiratory distress.Scientific reports · 2024Article
- Article
- Comprehensive Tools of Alkaloid/Volatile Compounds-Metabolomics and DNA Profiles: Bioassay-Role-Guided Differentiation Process of SixPharmaceuticals (Basel, Switzerland) · 2024Article
- Fighting cytokine storm and immunomodulatory deficiency: By using natural products therapy up to now.Frontiers in pharmacology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesNatural products are often efficacious and safe alternatives to synthetic drugs. This study explored secondary leaves and bark metabolites profiles in extracts of a new Egyptian hybrid, Annona cherimola × Annona squamosa, known as Abdel Razek. This hybrid exhibited 100% similarity with A. cherimola as evidenced by random amplified polymorphic DNA (RAPD) and inter-simple sequence repeat (ISSR) analyses.
methodsPrimary constituents in methanol extracts of different plant organs were identified. Extracts richest in alkaloids and polyphenolics were assessed for in vitro antioxidant activity and the most potent were further studied in vivo for treating gastric ulcer in rats. The latter activity was assessed histopathologically.
resultsStructural analysis with HPLC/ESI-MS
conclusionExtracts of Annona Abdel Razek had showed in vitro antioxidant effect and may be promising for the treatment of gastric ulcers.
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