Evidence map›Paper›PMID 35781841›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2022

The role of comorbid depressive symptoms on long-range temporal correlations in resting EEG in adults with ADHD.

Jue Huang, Eike Ahlers, Holger Bogatsch, Pierre Böhme, Thomas Ethofer, Andreas J Fallgatter, Jürgen Gallinat, Ulrich Hegerl, Isabella Heuser, Knut Hoffmann and 6 more

Open access · hybridAbstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Jue HuangDepartment of Psychiatry and Psychotherapy, University of Leipzig, 04103, Leipzig, Germany. jue.huang@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0003-1830-9340
Eike AhlersDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, 10117, Berlin, Germany.
Holger BogatschClinical Trial Centre Leipzig, Faculty of Medicine, University of Leipzig, 04107, Leipzig, Germany.
Pierre BöhmeDepartment of Psychiatry Psychotherapy and Preventive Medicine, University Hospital of Bochum, 44791, Bochum, Germany.
Thomas EthoferDepartment of Biomedical Magnetic Resonance, University Hospital of Tübingen, 72076, Tübingen, Germany.
Andreas J FallgatterDepartment of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, 72076, Tübingen, Germany.
Jürgen GallinatDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.
Ulrich HegerlDepartment of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital of Frankfurt - Goethe University, 60528, Frankfurt am Main, Germany.
Isabella HeuserDepartment of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, 10117, Berlin, Germany.
Knut HoffmannDepartment of Psychiatry Psychotherapy and Preventive Medicine, University Hospital of Bochum, 44791, Bochum, Germany.
Sarah Kittel-SchneiderDepartment of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital of Frankfurt - Goethe University, 60528, Frankfurt am Main, Germany.
Andreas ReifDepartment of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital of Frankfurt - Goethe University, 60528, Frankfurt am Main, Germany.
Daniel SchöttleDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20251, Hamburg, Germany.
Stefan UntereckerDepartment of Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Würzburg, 97080, Würzburg, Germany.
Matti Gärtner *Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, 10117, Berlin, Germany.
Maria Strauß *Department of Psychiatry and Psychotherapy, University of Leipzig, 04103, Leipzig, Germany.
Goethe University Frankfurt · DELeipzig University · DECharité - Universitätsmedizin Berlin · DEUniversität Hamburg · DEUniversity Hospitals of the Ruhr-University of Bochum · DEUniversity of Tübingen · DEMSB Medical School Berlin · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder, characterized by core symptoms of inattention, hyperactivity and impulsivity. Comorbid depression is commonly observed in ADHD-patients. Psychostimulants are recommended as first-line treatment for ADHD. Aberrant long-range temporal correlations (LRTCs) of neuronal activities in resting-state are known to be associated with disorganized thinking and concentrating difficulties (typical in ADHD) and with maladaptive thinking (typical in depression). It has yet to be examined whether (1) LRTC occur in ADHD-patients, and if so, (2) whether LRTC might be a competent biomarker in ADHD comorbid with current depression and (3) how depression affects psychostimulant therapy of ADHD symptoms. The present study registered and compared LRTCs in different EEG frequency bands in 85 adults with ADHD between groups with (n = 28) and without (n = 57) additional depressive symptoms at baseline. Treatment-related changes in ADHD, depressive symptoms and LRTC were investigated in the whole population and within each group. Our results revealed significant LRTCs existed in all investigated frequency bands. There were, however, no significant LRTC-differences between ADHD-patients with and without depressive symptoms at baseline and no LRTC-changes following treatment. However, depressed ADHD patients did seem to benefit more from the therapy with psychostimulant based on self-report.

Indexed as

Attention Deficit Disorder with HyperactivityAdultComorbidityDepressionElectroencephalographyHumansRestADHDDepressionEEGLong-range temporal correlationLRTCResting state

Identifiers

PMID35781841
PMCPMC9653316
OpenAlexW4283794356

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.