Evidence map›Paper›PMID 35781696›Full record

ArticleMagnetic resonance in medicine2022

A workflow for predicting temperature increase at the electrical contacts of deep brain stimulation electrodes undergoing MRI.

Alireza Sadeghi-Tarakameh, Nur Izzati Huda Zulkarnain, Xiaoxuan He, Ergin Atalar, Noam Harel, Yigitcan Eryaman

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alireza Sadeghi-TarakamehCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-5718-6553
Nur Izzati Huda ZulkarnainCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA.
Xiaoxuan HeCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0003-0885-912X
Ergin AtalarDepartment of Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey.ORCID 0000-0002-6874-6103
Noam HarelCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA.
Yigitcan EryamanCenter for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota, USA.
University of Minnesota · USBilkent University · TR

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Elementary Neuronal Ensembles to Whole Brain Networks: Ultrahigh Resolution Imaging of Function and Connectivity in Humans - SUPPLEMENTU01EB025144 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2017 to 2022
$9.7M
Safe Magnetic Resonance Imaging of Patients with Deep Brain Stimulation SystemsR01NS115180 · NINDS · UNIVERSITY OF MINNESOTA · PI ERYAMAN, YIGITCAN · 2020 to 2024
$1.9M
NIBIB NIH HHS P41 EB027061NIBIB NIH HHS U01 EB025144NINDS NIH HHS R01 NS115180
6 · The paper itself

Abstract

purposeThe purpose of this study is to present a workflow for predicting the radiofrequency (RF) heating around the contacts of a deep brain stimulation (DBS) lead during an MRI scan.

methodsThe induced RF current on the DBS lead accumulates electric charge on the metallic contacts, which may cause a high local specific absorption rate (SAR), and therefore, heating. The accumulated charge was modeled by imposing a voltage boundary condition on the contacts in a quasi-static electromagnetic (EM) simulation allowing thermal simulations to be performed with the resulting SAR distributions. Estimating SAR and temperature increases from a lead in vivo through EM simulation is not practical given anatomic differences and variations in lead geometry. To overcome this limitation, a new parameter, transimpedance, was defined to characterize a given lead. By combining the transimpedance, which can be measured in a single calibration scan, along with MR-based current measurements of the lead in a unique orientation and anatomy, local heating can be estimated. Heating determined with this approach was compared with results from heating studies of a commercial DBS electrode in a gel phantom with different lead configurations to validate the proposed method.

resultsUsing data from a single calibration experiment, the transimpedance of a commercial DBS electrode (directional lead, Infinity DBS system, Abbott Laboratories, Chicago, IL) was determined to be 88 Ω. Heating predictions using the DBS transimpedance and rapidly acquired MR-based current measurements in 26 different lead configurations resulted in a <23% (on average 11.3%) normalized root-mean-square error compared to experimental heating measurements during RF scans.

conclusionIn this study, a workflow consisting of an MR-based current measurement on the DBS lead and simple quasi-static EM/thermal simulations to predict the temperature increase around a DBS electrode undergoing an MRI scan is proposed and validated using a commercial DBS electrode.

Indexed as

Deep Brain StimulationElectrodesElectrodes, ImplantedMagnetic Resonance ImagingPhantoms, ImagingRadio WavesTemperatureWorkflowdeep brain stimulation safetyMRIradiofrequency heatingtemperature prediction

Identifiers

PMID35781696
PMCPMC9545305
OpenAlexW4283802891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.